Pulmonary vascular disease

Myeloid-cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice
Marija Gredic, Cheng-Yu Wu, Stefan Hadzic, Oleg Pak, Rajkumar Savai, Baktybek Kojonazarov, Siddartha Doswada, Astrid Weiss, Andreas Weigert, Andreas Guenther, Ralf P. Brandes, Ralph T. Schermuly, Friedrich Grimminger, Werner Seeger, Natascha Sommer, Simone Kraut, Norbert Weissmann

European Respiratory Journal Apr 2022, 59 (4) 2101153; DOI: 10.1183/13993003.01153-2021
Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension
Mark Toshner, Colin Church, Lars Harbaum, Christopher Rhodes, Sofia S. Villar Moreschi, James Liley, Rowena Jones, Amit Arora, Ken Batai, Ankit A. Desai, John G. Coghlan, J. Simon R. Gibbs, Dee Gor, Stefan Gräf, Louise Harlow, Jules Hernandez-Sanchez, Luke S. Howard, Marc Humbert, Jason Karnes, David G. Kiely, Rick Kittles, Emily Knightbridge, Brian Lam, Katie A. Lutz, William C. Nichols, Michael W. Pauciulo, Joanna Pepke-Zaba, Jay Suntharalingam, Florent Soubrier, Richard C. Trembath, Tae-Hwi L. Schwantes-An, S. John Wort, Martin R. Wilkins, Sean Gaine, Nicholas W. Morrell, Paul A. Corris

European Respiratory Journal Mar 2022, 59 (3) 2002463; DOI: 10.1183/13993003.02463-2020
Randomised controlled trial of a prognostic assessment and management pathway to reduce the length of hospital stay in normotensive patients with acute pulmonary embolism
David Jiménez, Carmen Rodríguez, Francisco León, Luis Jara-Palomares, Raquel López-Reyes, Pedro Ruiz-Artacho, Teresa Elías, Remedios Otero, Alberto García-Ortega, Agustina Rivas-Guerrero, Jaime Abelaira, Sonia Jiménez, Alfonso Muriel, Raquel Morillo, Deisy Barrios, Raphael Le Mao, Roger D. Yusen, Behnood Bikdeli, Manuel Monreal, José Luis Lobo

European Respiratory Journal Feb 2022, 59 (2) 2100412; DOI: 10.1183/13993003.00412-2021
Mild pulmonary hypertension and premature mortality among 154 956 men and women undergoing routine echocardiography
Simon Stewart, Yih-Kai Chan, David Playford, Geoffrey A. Strange

European Respiratory Journal Jan 2022, 59 (1) 2100832; DOI: 10.1183/13993003.00832-2021
Characterisation of paediatric pulmonary hypertensive vascular disease from the PPHNet Registry
Steven H. Abman, Mary P. Mullen, Lynn A. Sleeper, Eric D. Austin, Erika B. Rosenzweig, John P. Kinsella, Dunbar Ivy, Rachel K. Hopper, J. Usha Raj, Jeffrey Fineman, Roberta L. Keller, Angela Bates, Usha S. Krishnan, Catherine M. Avitabile, Alexander Davidson, Marc D. Natter, Kenneth D. Mandl

European Respiratory Journal Jan 2022, 59 (1) 2003337; DOI: 10.1183/13993003.03337-2020
Evolution of CT findings after anticoagulant treatment for acute pulmonary embolism in patients with and without an ultimate diagnosis of chronic thromboembolic pulmonary hypertension
Natalia J. Braams, Gudula J.A.M. Boon, Frances S. de Man, Josien van Es, Paul L. den Exter, Lucia J.M. Kroft, Ludo F.M. Beenen, Menno V. Huisman, Esther J. Nossent, Anco Boonstra, Anton Vonk Noordegraaf, Dieuwertje Ruigrok, Frederikus A. Klok, Harm Jan Bogaard, Lilian J. Meijboom

European Respiratory Journal Dec 2021, 58 (6) 2100699; DOI: 10.1183/13993003.00699-2021
Role of angiopoietin-2 in venous thrombus resolution and chronic thromboembolic disease
Lukas Hobohm, Sebastian Kölmel, Caroline Niemann, Philipp Kümpers, Valentin J. Krieg, Magdalena L. Bochenek, Alexander H. Lukasz, Yvonne Reiss, Karl-Heinz Plate, Christoph Liebetrau, Christoph B. Wiedenroth, Stefan Guth, Thomas Münzel, Gerd Hasenfuß, Philip Wenzel, Eckhard Mayer, Stavros V. Konstantinides, Katrin Schäfer, Mareike Lankeit

European Respiratory Journal Dec 2021, 58 (6) 2004196; DOI: 10.1183/13993003.04196-2020
Involvement of CFTR in the pathogenesis of pulmonary arterial hypertension
Hélène Le Ribeuz, Lucie To, Maria-Rosa Ghigna, Clémence Martin, Chandran Nagaraj, Elise Dreano, Catherine Rucker-Martin, Barbara Girerd, Jérôme Bouligand, Christine Pechoux, Mélanie Lambert, Angèle Boet, Justin Issard, Olaf Mercier, Konrad Hoetzenecker, Boris Manoury, Frédéric Becq, Pierre-Régis Burgel, Charles-Henry Cottart, Andrea Olschewski, Isabelle Sermet-Gaudelus, Frédéric Perros, Marc Humbert, David Montani, Fabrice Antigny

European Respiratory Journal Nov 2021, 58 (5) 2000653; DOI: 10.1183/13993003.00653-2020
Outcomes of patients with decreased arterial oxyhaemoglobin saturation on pulmonary arterial hypertension drugs
Simon Valentin, Arnaud Maurac, Olivier Sitbon, Antoine Beurnier, Emmanuel Gomez, Anne Guillaumot, Laura Textoris, Renaud Fay, Laurent Savale, Xavier Jaïs, David Montani, François Picard, Jean-François Mornex, Grégoire Prevot, François Chabot, Marc Humbert, Ari Chaouat

European Respiratory Journal Nov 2021, 58 (5) 2004066; DOI: 10.1183/13993003.04066-2020
Trends in risk stratification, in-hospital management and mortality of patients with acute pulmonary embolism: an analysis from the China pUlmonary thromboembolism REgistry Study (CURES)
Zhenguo Zhai, Dingyi Wang, Jieping Lei, Yuanhua Yang, Xiaomao Xu, Yingqun Ji, Qun Yi, Hong Chen, Xiaoyun Hu, Zhihong Liu, Yimin Mao, Jie Zhang, Juhong Shi, Zhu Zhang, Sinan Wu, Qian Gao, Xincao Tao, Wanmu Xie, Jun Wan, Yunxia Zhang, Shuai Zhang, Kaiyuan Zhen, Zhonghe Zhang, Baomin Fang, Chen Wang

European Respiratory Journal Oct 2021, 58 (4) 2002963; DOI: 10.1183/13993003.02963-2020

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