Mechanisms of lung disease

Mechanisms of lung disease

The mucus bundles responsible for airway cleaning are retained in cystic fibrosis and by cholinergic stimulation
Anna Ermund, Lauren N. Meiss, Brendan Dolan, Andrea Bähr, Nikolai Klymiuk, Gunnar C. Hansson

European Respiratory Journal Aug 2018, 52 (2) 1800457; DOI: 10.1183/13993003.00457-2018
Reptin drives tumour progression and resistance to chemotherapy in nonsmall cell lung cancer
Jan-Henrik Mikesch, Daniela Schwammbach, Wolfgang Hartmann, Lars H. Schmidt, Christoph Schliemann, Linus Angenendt, Rainer Wiewrodt, Alessandro Marra, Nils H. Thoennissen, Eva Wardelmann, Gabriele Köhler, Georg Lenz, Carsten Müller-Tidow, Wolfgang E. Berdel, Maria-Francisca Arteaga

European Respiratory Journal Jul 2018, 52 (1) 1701637; DOI: 10.1183/13993003.01637-2017
Fibroblast growth factor 23 and Klotho contribute to airway inflammation
Stefanie Krick, Alexander Grabner, Nathalie Baumlin, Christopher Yanucil, Scott Helton, Astrid Grosche, Juliette Sailland, Patrick Geraghty, Liliana Viera, Derek W. Russell, J. Michael Wells, Xin Xu, Amit Gaggar, Jarrod Barnes, Gwendalyn D. King, Michael Campos, Christian Faul, Matthias Salathe

European Respiratory Journal Jul 2018, 52 (1) 1800236; DOI: 10.1183/13993003.00236-2018
In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss
Igor L. Chernyavsky, Richard J. Russell, Ruth M. Saunders, Gavin E. Morris, Rachid Berair, Amisha Singapuri, Latifa Chachi, Adel H. Mansur, Peter H. Howarth, Patrick Dennison, Rekha Chaudhuri, Stephen Bicknell, Felicity R.A.J. Rose, Salman Siddiqui, Bindi S. Brook, Christopher E. Brightling

European Respiratory Journal May 2018, 51 (5) 1701680; DOI: 10.1183/13993003.01680-2017
Rates of change in FEV₁ and D_LCO as potential indicators for mTOR inhibitor therapy in premenopausal lymphangioleiomyomatosis patients
Angelo M. Taveira-DaSilva, Patricia Julien-Williams, Amanda M. Jones, Mario Stylianou, Joel Moss

European Respiratory Journal Apr 2018, 51 (4) 1702258; DOI: 10.1183/13993003.02258-2017
Dasatinib increases endothelial permeability leading to pleural effusion
Carole Phan, Etienne-Marie Jutant, Ly Tu, Raphaël Thuillet, Andrei Seferian, David Montani, Alice Huertas, Jan van Bezu, Fabian Breijer, Anton Vonk Noordegraaf, Marc Humbert, Jurjan Aman, Christophe Guignabert

European Respiratory Journal Jan 2018, 51 (1) 1701096; DOI: 10.1183/13993003.01096-2017
Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations
Olivier Le Rouzic, Muriel Pichavant, Emilie Frealle, Antoine Guillon, Mustapha Si-Tahar, Philippe Gosset

European Respiratory Journal Oct 2017, 50 (4) 1602434; DOI: 10.1183/13993003.02434-2016
New drug targets for chronic cough: research you can literally sink your teeth into!
Caroline J. Jolley, Surinder S. Birring

European Respiratory Journal Sep 2017, 50 (3) 1701571; DOI: 10.1183/13993003.01571-2017
TRPA1 activation in a human sensory neuronal model: relevance to cough hypersensitivity?
Rebecca Clarke, Kevin Monaghan, Imad About, Caoimhin S. Griffin, Gerard P. Sergeant, Ikhlas El Karim, J. Graham McGeown, S. Louise Cosby, Timothy M. Curtis, Lorcan P. McGarvey, Fionnuala T. Lundy

European Respiratory Journal Sep 2017, 50 (3) 1700995; DOI: 10.1183/13993003.00995-2017
Mechanistic insight into the function of the microbiome in lung diseases
Niki D.J. Ubags, Benjamin J. Marsland

European Respiratory Journal Sep 2017, 50 (3) 1602467; DOI: 10.1183/13993003.02467-2016

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