Asthma and allergy

Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis
Kay Wang, Jan Y. Verbakel, Jason Oke, Alexander Fleming-Nouri, Josh Brewin, Nia Roberts, Norihiro Harada, Ryo Atsuta, Kazuhisa Takahashi, Kazutaka Mori, Tomoyuki Fujisawa, Toshihiro Shirai, Tomotaka Kawayama, Hiromasa Inoue, Stephen Lazarus, Stanley Szefler, Fernando Martinez, Dominick Shaw, Ian D. Pavord, Mike Thomas

European Respiratory Journal May 2020, 55 (5) 1902150; DOI: 10.1183/13993003.02150-2019
Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma?
Shona S. Fielding, Marielle Pijnenburg, Johan de Jongste, Katherine Pike, Graham Roberts, Helen Petsky, Anne B. Chang, Maria Fritsch, Thomas Frischer, Stanley J. Szefler, Peter Gergen, Francoise Vermeulen, Robin Vael, Steve S. Turner

European Respiratory Journal May 2020, 55 (5) 1901879; DOI: 10.1183/13993003.01879-2019
Mepolizumab effectiveness and identification of super-responders in severe asthma
Erin S. Harvey, David Langton, Constance Katelaris, Sean Stevens, Claude S. Farah, Andrew Gillman, John Harrington, Mark Hew, Vicky Kritikos, Naghmeh Radhakrishna, Philip Bardin, Matthew Peters, Paul N. Reynolds, John W. Upham, Melissa Baraket, Simon Bowler, Jeffrey Bowden, Jimmy Chien, Li Ping Chung, Christopher Grainge, Christine Jenkins, Gregory P. Katsoulotos, Joy Lee, Vanessa M. McDonald, Helen K. Reddel, Janet Rimmer, Peter A.B. Wark, Peter G. Gibson

European Respiratory Journal May 2020, 55 (5) 1902420; DOI: 10.1183/13993003.02420-2019
Aberrant anti-viral response of natural killer cells in severe asthma
Justine Devulder, Cécile Chenivesse, Valérie Ledroit, Stéphanie Fry, Pierre-Emmanuel Lobert, Didier Hober, Anne Tsicopoulos, Catherine Duez

European Respiratory Journal May 2020, 55 (5) 1802422; DOI: 10.1183/13993003.02422-2018
Adherence to inhaled corticosteroids and clinical outcomes in mepolizumab therapy for severe asthma
Gráinne d'Ancona, Joanne Kavanagh, Cris Roxas, Linda Green, Mariana Fernandes, Louise Thomson, Jaideep Dhariwal, Alexandra M. Nanzer, David J. Jackson, Brian D. Kent

European Respiratory Journal May 2020, 55 (5) 1902259; DOI: 10.1183/13993003.02259-2019
Looking back to go forward: adherence to inhaled therapy before biologic therapy in severe asthma
Richard W. Costello, Breda Cushen

European Respiratory Journal May 2020, 55 (5) 2000954; DOI: 10.1183/13993003.00954-2020
Early-life antibiotic use and risk of asthma and eczema: results of a discordant twin study
Elise M.A. Slob, Bronwyn K. Brew, Susanne J.H. Vijverberg, Chantal J.A.R. Kats, Cristina Longo, Mariëlle W. Pijnenburg, Toos C.E.M. van Beijsterveldt, Conor V. Dolan, Meike Bartels, Patrick Magnusson, Paul Lichtenstein, Tong Gong, Gerard H. Koppelman, Catarina Almqvist, Dorret I. Boomsma, Anke H. Maitland-van der Zee

European Respiratory Journal Apr 2020, 55 (4) 1902021; DOI: 10.1183/13993003.02021-2019
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
Md. Khadem Ali, Richard Y. Kim, Alexandra C. Brown, Jemma R. Mayall, Rafia Karim, James W. Pinkerton, Gang Liu, Kristy L. Martin, Malcolm R. Starkey, Amber L. Pillar, Chantal Donovan, Prabuddha S. Pathinayake, Olivia R. Carroll, Debbie Trinder, Hock L. Tay, Yusef E. Badi, Nazanin Z. Kermani, Yi-Ke Guo, Ritambhara Aryal, Sharon Mumby, Stelios Pavlidis, Ian M. Adcock, Jessica Weaver, Dikaia Xenaki, Brian G. Oliver, Elizabeth G. Holliday, Paul S. Foster, Peter A. Wark, Daniel M. Johnstone, Elizabeth A. Milward, Philip M. Hansbro, Jay C. Horvat

European Respiratory Journal Apr 2020, 55 (4) 1901340; DOI: 10.1183/13993003.01340-2019
Overuse of short-acting β₂-agonists in asthma is associated with increased risk of exacerbation and mortality: a nationwide cohort study of the global SABINA programme
Bright I. Nwaru, Magnus Ekström, Pål Hasvold, Fredrik Wiklund, Gunilla Telg, Christer Janson

European Respiratory Journal Apr 2020, 55 (4) 1901872; DOI: 10.1183/13993003.01872-2019
Patient preferences for symptom-driven or regular preventer treatment in mild to moderate asthma: findings from the PRACTICAL study, a randomised clinical trial
Christina Baggott, Helen K. Reddel, Jo Hardy, Jenny Sparks, Mark Holliday, Andrew Corin, Barney Montgomery, Jim Reid, Davitt Sheahan, Robert J. Hancox, Mark Weatherall, Richard Beasley, James Fingleton

European Respiratory Journal Apr 2020, 55 (4) 1902073; DOI: 10.1183/13993003.02073-2019

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