Negligible clearance of ultrafine particles retained in healthy and affected human lungs

P Wiebert, A Sanchez-Crespo, J Seitz… - European …, 2006 - Eur Respiratory Soc
Ambient particles are believed to be a specific health hazard, although the underlying
mechanisms are not fully understood. There are data in the literature indicating fast and …

Deposition, retention, and translocation of ultrafine particles from the central airways and lung periphery

W Moller, K Felten, K Sommerer… - American journal of …, 2008 - atsjournals.org
Rationale: Little is known about clearance of ultrafine carbon particles from the different
regions of the human lung. These particles may accumulate and present a health hazard …

No significant translocation of inhaled 35-nm carbon particles to the circulation in humans

P Wiebert, A Sanchez-Crespo, R Falk… - Inhalation …, 2006 - Taylor & Francis
Human pulmonary retention of 35 nm 99mTc-labeled carbonaceous particles, produced with
a modified Technegas generator, was followed for 24 h using a gamma camera imaging …

Ultrafine particle deposition and clearance in the healthy and obstructed lung

JS Brown, KL Zeman, WD Bennett - American journal of respiratory …, 2002 - atsjournals.org
Numerous epidemiologic studies have shown associations between exposure to particulate
air pollution and acute increases in morbidity and mortality, particularly in persons with …

Pulmonary tissue access of ultrafine particles

J FERIN, G OBERDÖRSTER… - Journal of aerosol …, 1991 - liebertpub.com
Rats were exposed to different sizes of Ti02 or AI2O3 particles by intratracheal instillation or
by aerosol inhalation. The lungs were analyzed at days 1, 29 and 59 or 60 after exposure for …

Translocation and effects of ultrafine particles outside of the lung.

A Elder, G Oberdörster - Clinics in occupational and environmental …, 2006 - europepmc.org
Ultrafine, or nano-, particles (< 100 nm) have been associated in epidemiological, human
clinical, and animal studies with adverse cardiopulmonary outcomes. Deposition of inhaled …

The long-term clearance kinetics of insoluble particles from the human lung

MR Bailey, FA Fry, AC James - Inhaled Particles V, 1982 - Elsevier
Seven volunteers inhaled monodisperse 1.2 and 3.9 μm dia.(1.9 and 6.1 μm equivalent
aerodynamic diameter) fused aluminosilicate particles labelled with 85 Sr and 88 Y …

Development of a physiologically based kinetic model for 99m-Technetium-labelled carbon nanoparticles inhaled by humans

ARR Péry, C Brochot, PHM Hoet, A Nemmar… - Inhalation …, 2009 - Taylor & Francis
Particulate air pollution is associated with respiratory and cardiovascular morbidity and
mortality. Recent studies investigated whether and to which extent inhaled ultrafine particles …

[CITATION][C] Increased pulmonary toxicity of ultrafine particles? I. Particle clearance, translocation, morphology

J Ferin, G Oberdörster, DP Penney… - Journal of Aerosol …, 1990 - Elsevier
Based on the most pronounced pathologic effect of dust on the lung tissue, particles are
considered to be fibrogenic or non-fibrogenic. The non-fibrogenic or'nuisance'particles have …

Respiratory tract deposition of ultrafine particles in subjects with obstructive or restrictive lung disease

PJ Anderson, JD Wilson, FC Hiller - Chest, 1990 - Elsevier
To evaluate the effects of lung disease on deposition of inhaled ultrafine particles (< 0.1 μm
diameter), we measured total respiratory tract deposition of nonhygroscopic particles of 0.02 …