Idiopathic pulmonary fibrosis: treatment options in pursuit of evidence-based approaches

G Raghu - European Respiratory Journal, 2006 - Eur Respiratory Soc
The long-standing need to determine an effective medical treatment regimen with clinically
significant and relevant end-points to improve outcome for patients with idiopathic …

Clinical trials in idiopathic pulmonary fibrosis: a word of caution concerning choice of outcome measures

WC Johnson, G Raghu - European Respiratory Journal, 2005 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a challenging and frustrating disease for clinicians and
patients confronted with this clinical entity, since it is associated with a dismal, 3-yr median …

Therapeutic management of idiopathic pulmonary fibrosis: an evidence-based approach

SD Nathan - Clinics in chest medicine, 2006 - chestmed.theclinics.com
Idiopathic pulmonary fibrosis (IPF), also known as cryptogenic fibrosing alveolitis, is a
distinct form of interstitial lung disease of unknown etiology that is limited to the lung; it is …

The big clinical trials in idiopathic pulmonary fibrosis

F Luppi, P Spagnolo, S Cerri… - Current opinion in …, 2012 - journals.lww.com
Despite multiple clinical trials, there is no strong, definitive evidence in favor of any agent to
treat IPF. On the other hand, the placebo arms of these large trials have provided us with …

[HTML][HTML] Idiopathic pulmonary fibrosis: from clinical trials to real-life experiences

S Harari, A Caminati - European Respiratory Review, 2015 - Eur Respiratory Soc
Randomised controlled clinical trials are fundamental in medicine to develop new effective
drugs and new therapeutic regimens and are the strength of evidence-based medicine …

Current and future therapeutic approaches in idiopathic pulmonary fibrosis

D Bouros, KM Antoniou - European Respiratory Journal, 2005 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a lethal form of idiopathic diffuse lung disorders for
which no current treatment is effective. The aim of the present study was to systematically …

Idiopathic pulmonary fibrosis: guidelines for diagnosis and clinical management have advanced from consensus-based in 2000 to evidence-based in 2011

G Raghu - European Respiratory Journal, 2011 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is increasingly recog-nised as a well-known clinical and
highly complex entity associated with poor prognosis and a median survival of 3–5 yrs after …

A new era in idiopathic pulmonary fibrosis: considerations for future clinical trials

HR Collard, WZ Bradford, V Cottin… - European …, 2015 - Eur Respiratory Soc
The past decade has seen substantial progress in understanding the pathobiology, natural
history, and clinical significance of idiopathic pulmonary fibrosis (IPF), culminating in the …

Management of idiopathic pulmonary fibrosis

S Cerri, P Spagnolo, F Luppi… - Clinics in Chest …, 2012 - chestmed.theclinics.com
Idiopathic pulmonary fibrosis (IPF) represents one of the most challenging diseases for chest
physicians. The diagnostic process is complex and requires close interaction with different …

Treatment of idiopathic pulmonary fibrosis

CE Daniels, JH Ryu - … in Respiratory and Critical Care Medicine, 2006 - thieme-connect.com
Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive lung disease in most cases,
and effective treatment is still lacking. This review examines the current status of treatment …