Objective To evaluate risk factors for severe outcomes in patients with seasonal and pandemic
influenza. Design Systematic review. Study selection Observational studies reporting on …

Background Working in healthcare is often considered a risk factor for influenza; however,
this risk has not been quantified. We aimed to systematically review evidence describing the …

Objectives Antibiotics are commonly classified into bactericidal and bacteriostatic agents
based on their antimicrobial action. We aimed to assess whether this distinction is clinically …

Background. Invasive Mycobacterium chimaera infections were diagnosed in 2012 in 2 heart
surgery patients on extracorporeal circulation. We launched an outbreak investigation to …

Aims We identified 10 patients with disseminated Mycobacterium chimaera infections
subsequent to open-heart surgery at three European Hospitals. Infections originated from the …

ObjectiveThe preventable proportion of healthcare-associated infections (HAIs) may
decrease over time as standards of care improve. We aimed to assess the proportion of HAIs …

Background: Reports on antibiotic use often lack complete definitions of the units of measurement,
hampering the comparison of data between hospitals or hospital units. Patients and …

Heater–cooler units (HCUs) were recently identified as a source of Mycobacterium chimaera
causing surgical site infections. We investigated transmission of this bacterium from HCUs …

Background Unnecessary or inappropriate use of antimicrobials is associated with the
emergence of antimicrobial resistance, drug toxicity, increased morbidity and health care costs. …

This systematic review and meta-analysis compared the efficacy and toxicity of dexamethasone
(DEX) versus prednisone (PRED) for induction therapy in childhood acute lymphoblastic …