The burden of food allergy on children and teens: a systematic review

…, S Ahlstedt, R Middelveld… - Pediatric Allergy and …, 2022 - Wiley Online Library
Background Over the last two decades, researchers have placed increasing attention on
understanding how food allergy affects the health‐related quality of life (HRQL) and …

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

…, JG Matthews, R Middelveld… - European …, 2015 - Eur Respiratory Soc
U-BIOPRED is a European Union consortium of 20 academic institutions, 11 pharmaceutical
companies and six patient organisations with the objective of improving the understanding …

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

…, A Menzies-Gow, L Metcalf, R Middelveld… - Journal of Allergy and …, 2017 - Elsevier
Background Asthma is a heterogeneous disease in which there is a differential response to
asthma treatments. This heterogeneity needs to be evaluated so that a personalized …

A scoping review of the caregiver burden of pediatric food allergy

MA Golding, NV Gunnarsson, R Middelveld… - Annals of Allergy …, 2021 - Elsevier
Objective Although a number of articles have described the psychosocial impact of raising a
child with a food allergy, recent attempts at synthesizing this literature have been narrow in …

[HTML][HTML] Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

…, A Mazein, A Meiser, RJM Middelveld… - Journal of allergy and …, 2019 - Elsevier
Background Although several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R)
to asthma severity and decreased lung function, the role of IL-6 trans-signaling (IL-6TS) in …

[HTML][HTML] Increased Prevalence of Symptoms of Rhinitis but Not of Asthma between 1990 and 2008 in Swedish Adults: Comparisons of the ECRHS and GA2LEN …

A Bjerg, L Ekerljung, R Middelveld, SE Dahlén… - PloS one, 2011 - journals.plos.org
Background The increase in asthma prevalence until 1990 has been well described.
Thereafter, time trends are poorly known, due to the low number of high quality studies. The …

Pathway discovery using transcriptomic profiles in adult-onset severe asthma

…, A Mazein, A Meiser, RJM Middelveld… - Journal of Allergy and …, 2018 - Elsevier
Background Adult-onset severe asthma is characterized by highly symptomatic disease
despite high-intensity asthma treatments. Understanding of the underlying pathways of this …

IL-17–high asthma with features of a psoriasis immunophenotype

…, A Mazein, A Meiser, RJM Middelveld… - Journal of Allergy and …, 2019 - Elsevier
… Correlations were tested with Spearman r statistics. Gene expression data from blood
were analyzed by using topological data analysis (TDA) performed in Ayasdi Core software (…

Staphylococcus aureus enterotoxin‐specific IgE is associated with asthma in the general population: a GA2LEN study

…, U Krämer, PM Matricardi, RJM Middelveld… - Allergy, 2013 - Wiley Online Library
Background Specific IgE to S taphylococcus aureus enterotoxins ( SE ‐IgE) has been
associated with asthma. In the general population, we aimed to determine the prevalence of and …

Chronic rhinosinusitis in asthma is a negative predictor of quality of life: results from the Swedish GA2LEN survey

A Ek, RJM Middelveld, H Bertilsson, A Bjerg… - Allergy, 2013 - Wiley Online Library
Background Asthma and chronic rhinosinusitis ( CRS ) both impair quality of life, but the
quality‐of‐life impact of comorbid asthma and CRS is poorly known. The aim of this study was to …