Serine proteases released from neutrophils are central to the pathogenesis of cystic fibrosis
lung disease and are considered to be obvious therapeutic targets. Neutrophil elastase …

LB-294 Proteomics were employed to measure proteins expressed in the urines of female
Fischer-344 rats. Urines were collected from rats bearing large (>200 mg) bladder tumors …

Molecular markers for the development and response of tumors to agents are essential for
efficacy assessment of cancer chemoprevention. The discovery, verification and validation of …

… with the mαPanNav antibody revealed that significantly (P < 0.05) more Nav-bound iFGF-A …
Li for maintaining the Fgf14 −/− mouse colony, P. Erdman-Gilmore and JP Malone for …

Deciphering the complex interplay of neutrophil extracellular traps (NETs) with the
surrounding environment is a challenge with notable clinical implications. To bridge the gap in …

Members of the pentraxin family, including PTX3 and serum amyloid P component (SAP),
have been reported to play a role in innate host defence against a range of microbial …

Site-1 protease (S1P) ablation in the osterix-lineage in mice drastically reduces bone
development and downregulates bone marrow-derived skeletal stem cells. Here we show that …

… fumigatus and P. aeruginosa. Infections are one of the main causes of morbidity and …
PTX3 reduces colonization and inflammation in models of aspergillosis and P. aeruginosa lung …

Onchocerca volvulus is the nematode pathogen responsible for human onchocerciasis also
known as “River blindness”, a neglected tropical disease that affects up to 18 million people …

Nematodes constitute a very successful phylum, especially in terms of parasitism. Inside
their mammalian hosts, parasitic nematodes mainly dwell in the digestive tract (geohelminths) …