… In addition, p-glycoprotein also designated the multidrug … toxicity towards p-glycoprotein
expressing tumor cells (p-glycoprotein … limit paclitaxel binding to p-glycoprotein and subsequent …

During the last few years, research on toxicologically relevant properties of engineered
nanoparticles has increased tremendously. A number of international research projects and …

… epithelial lung cells are able to generate intracellular ROS upon exposure to fly ash, DEP,
PM and quartz particles, processes in which mitochondrial respiration and activation of NAD(P)…

The revolution in nanotechnology is set to bring advantages in areas of our lives as diverse
as engineering, information technology, and diagnostics. Part of this will necessitate large …

A broad array of oxidative stresses modulates gene expression in a variety of mammalian
cells. One goal of this review was to characterize cellular responses to oxidative injury, how …

Ultrafine (Uf) particles are a component of particulate air pollution suggested to be responsible
for the health effects associated with elevations of this pollutant. We have previously …

Dissolution, translocation, and disposition have been shown to play a key role in the fate and
effects of inhaled particles and fibers. Concepts that have been applied in the micron size …

This review focuses on the potential role that oxidative stress plays in the adverse effects of
PM 10 . The central hypothesis is that the ability of PM 10 to cause oxidative stress underlies …

Nanoparticles (NP), here defined as particles with a diameter smaller then 100 nm, are
increasingly used in different applications, including drug carrier systems and to pass organ …

… ‘*’ Indicates that ascorbate or glutathione concentrations in the treatment groups were
significantly different (P < 0.05) than the 4h particle free control value; ‘a’ illustrates that the …