Mitochondrial KATP channels: role in cardioprotection
O Oldenburg, MV Cohen, DM Yellon… - Cardiovascular …, 2002 - academic.oup.com
The role of the mitochondrial ATP-sensitive potassium channel (mK ATP ) in ischemic
preconditioning and cardioprotection is reviewed. A great deal of accumulated evidence …
preconditioning and cardioprotection is reviewed. A great deal of accumulated evidence …
Sleep apnoea and the heart
… Each obstructive respiratory event is associated with an increase of the negative intrathoracic
pressure up to 60–70 cmH 2 O [129]. Also, hypoxic pulmonary vasoconstriction further …
pressure up to 60–70 cmH 2 O [129]. Also, hypoxic pulmonary vasoconstriction further …
The importance of sleep-disordered breathing in cardiovascular disease
Obstructive sleep apnoea and central sleep apnoea/Cheyne-Stokes respiration are
collectively referred to as sleep-disordered breathing (SDB). Rapidly accumulating evidence …
collectively referred to as sleep-disordered breathing (SDB). Rapidly accumulating evidence …
Sleep‐disordered breathing in patients with symptomatic heart failure A contemporary study of prevalence in and characteristics of 700 patients
O Oldenburg, B Lamp, L Faber… - European journal of …, 2007 - Wiley Online Library
Sleep‐disordered breathing in patients with symptomatic heart failure A contemporary study
of prevalence in and characteristics of 700 patients - Oldenburg - 2007 - European Journal …
of prevalence in and characteristics of 700 patients - Oldenburg - 2007 - European Journal …
Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection
O Oldenburg, Q Qin, T Krieg, XM Yang… - American Journal …, 2004 - journals.physiology.org
Bradykinin (BK) mimics ischemic preconditioning by generating reactive oxygen species (ROS).
To identify intermediate steps that lead to ROS generation, rabbit cardiomyocytes were …
To identify intermediate steps that lead to ROS generation, rabbit cardiomyocytes were …
Sleep‐disordered breathing in heart failure with normal left ventricular ejection fraction
…, C Langer, D Horstkotte, O Oldenburg - European journal of …, 2009 - Wiley Online Library
Aims In patients with systolic heart failure (SHF) a high prevalence of sleep‐disordered
breathing (SDB) has been documented. The purpose of this study was to investigate the …
breathing (SDB) has been documented. The purpose of this study was to investigate the …
Cheyne–Stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverter …
…, C Langer, D Horstkotte, O Oldenburg - European heart …, 2011 - academic.oup.com
Aims The aim of this first large-scale long-term study was to investigate whether obstructive
sleep apnoea (OSA) and/or central sleep apnoea (CSA) are associated with an increased …
sleep apnoea (OSA) and/or central sleep apnoea (CSA) are associated with an increased …
Nocturnal hypoxaemia is associated with increased mortality in stable heart failure patients
O Oldenburg, B Wellmann, A Buchholz… - European heart …, 2016 - academic.oup.com
Aim This study investigated the prognostic value of sleep-disordered breathing (SDB) in a
large cohort of patients with heart failure with reduced left ventricular function (HF-REF), with …
large cohort of patients with heart failure with reduced left ventricular function (HF-REF), with …
Prevalence and predictors of sleep-disordered breathing in patients with stable chronic heart failure: the SchlaHF registry
M Arzt, H Woehrle, O Oldenburg, A Graml, A Suling… - JACC: Heart Failure, 2016 - jacc.org
… Oldenburg has acted as a consultant for ResMed and Respicardia; has received a research
grant from ResMed; and has received lecture honoraria from ResMed, Respicardia, and …
grant from ResMed; and has received lecture honoraria from ResMed, Respicardia, and …
Cardiovascular outcomes with minute ventilation–targeted adaptive servo-ventilation therapy in heart failure: the CAT-HF trial
…, AB Blase, JA Lindenfeld, O Oldenburg - Journal of the American …, 2017 - jacc.org
Background : Sleep apnea is common in hospitalized heart failure (HF) patients and is
associated with increased morbidity and mortality. Objectives : The CAT-HF (Cardiovascular …
associated with increased morbidity and mortality. Objectives : The CAT-HF (Cardiovascular …