CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells
…, Y Morimoto, J Kumagai, A Onodera, N Mato… - Nature …, 2019 - nature.com
… c, Quantification of collagen protein in the lungs from control (n = 6) and Asp-Ag mice (n =
11… hi CD4 + T cells from control (n = 5) and Asp-Ag mice (n = 6). Representative findings from …
11… hi CD4 + T cells from control (n = 5) and Asp-Ag mice (n = 6). Representative findings from …
[HTML][HTML] Age-related and historical changes in the clinical characteristics of sarcoidosis in Japan
…, Y Sugiyama, Y Nakamura, M Nakayama, N Mato… - Respiratory …, 2015 - Elsevier
… We compared organ involvement between subgroups differentiated by sex and age (<45
years; n = 275; ≥45 years; n = 313) at diagnosis and identified historical changes in the age-…
years; n = 275; ≥45 years; n = 313) at diagnosis and identified historical changes in the age-…
[HTML][HTML] NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β
…, M Kobayashi, T Komada, Y Inoue, N Mato… - Journal of Biological …, 2015 - ASBMB
… to normoxia or hyperoxia for 72 h (n = 3–5 for each in normoxia, and n = 12–14 for each
in … to normoxia or hyperoxia for 72 h (n = 6 for each in normoxia, and n = 9–12 for each in …
in … to normoxia or hyperoxia for 72 h (n = 6 for each in normoxia, and n = 9–12 for each in …
The pathogenicity of IL-33 on steroid-resistant eosinophilic inflammation via the activation of memory-type ST2+CD4+ T cells
K Hirahara, N Mato, K Hagiwara… - Journal of leukocyte …, 2018 - academic.oup.com
The lungs are the primary organs of the respiratory system in many animals and have unique
epithelial barrier systems to protect the host from continuous invasion of various harmful …
epithelial barrier systems to protect the host from continuous invasion of various harmful …
Physical activity in patients with idiopathic pulmonary fibrosis
…, F Kurosaki, T Sawata, S Nakazawa, N Mato… - …, 2015 - Wiley Online Library
… For treatment, N-acetyl cysteine was administered to eight patients, pirfenidone to three
patients, prednisolone to two patients and long-term oxygen therapy to two patients. …
patients, prednisolone to two patients and long-term oxygen therapy to two patients. …
Optimization of adeno-associated virus vector-mediated gene transfer to the respiratory tract
F Kurosaki, R Uchibori, N Mato, Y Sehara, Y Saga… - Gene therapy, 2017 - nature.com
An efficient adeno-associated virus (AAV) vector was constructed for the treatment of respiratory
diseases. AAV serotypes, promoters and routes of administration potentially influencing …
diseases. AAV serotypes, promoters and routes of administration potentially influencing …
[HTML][HTML] Nutritional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation
…, U Seidel, J Geisel, T Kanno, J Kumagai, N Mato… - Scientific Reports, 2017 - nature.com
… The results show mean EAE score ± SEM from 2 independent experiments with n = 16 mice
(*P < 0.05 day 16 to 22; Wilcoxon test). (b) Mice were fed with CUR as in (a) and immunized …
(*P < 0.05 day 16 to 22; Wilcoxon test). (b) Mice were fed with CUR as in (a) and immunized …
Clinical features of pulmonary aspergillosis associated with interstitial pneumonia
F Kurosaki, M Bando, M Nakayama, N Mato… - Internal …, 2014 - jstage.jst.go.jp
… chronic pulmonary aspergillosis (n=14) and invasive pulmonary aspergillosis (n= 1)… n=9),
rheumatoid arthritisrelated interstitial pneumonia (n=4) and pleuroparenchymal fibroelastosis (n…
rheumatoid arthritisrelated interstitial pneumonia (n=4) and pleuroparenchymal fibroelastosis (n…
[HTML][HTML] Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid …
TJ Gaymes, AM Mohamedali, M Patterson, N Matto… - …, 2013 - ncbi.nlm.nih.gov
… However, due to the absence of an effective N-terminal CtIP antibody, we could not
entirely rule out the presence of an N-terminal 1–327 amino acid truncated CtIP protein. …
entirely rule out the presence of an N-terminal 1–327 amino acid truncated CtIP protein. …
Inflammasome-independent and atypical processing of IL-1β contributes to acid aspiration–induced acute lung injury
…, R Kamata, T Komada, N Mato… - The Journal of …, 2019 - journals.aai.org
… injury was performed (n = 3 for each in vehicle, n = 4 for each … h after the aspiration (n = 4
for each in vehicle, n = 9–11 for … 24 h after aspiration (n = 6 in vehicle, n = 12 in acid aspiration…
for each in vehicle, n = 9–11 for … 24 h after aspiration (n = 6 in vehicle, n = 12 in acid aspiration…