There is need for a validated short, simple instrument to quantify chronic obstructive
pulmonary disease (COPD) impact in routine practice to aid health status assessment and …

This study examined factors accounting for functional performance limitations in 100 long-term
survivors of allogeneic hematopoietic stem cell transplantation with chronic graft-versus-…

Abstract Knowledge about the pathogenesis and pathophysiology of chronic obstructive
pulmonary disease (COPD) has advanced dramatically over the last 30 years. Unfortunately, …

Objective: Although chronic and subacute cough are clinically problematic and a target of
therapeutic interventions, there are no validated cough severity patient-reported outcome (PRO…

Hans Selye's theoretical propositions and empirical findings provided many of the principles
currently used in stress research, and are often cited as scientific bases for nursing theory, …

… Leidy’s model of function clearly outlines and defines the elements of functional status. In
contrast to the disability cascade, Leidy’s conceptualization keeps capacity and performance …

Recently, the FDA has encouraged testing of medications among pediatric patients during
drug development. Pharmaceutical companies have responded by conducting more clinical …

The importance of content validity in developing patient reported outcomes (PRO) instruments
is stressed by both the US Food and Drug Administration and the European Medicines …

… Gwaltney PhD 3 , Nancy Kline Leidy PhD 4 , Mona L. Martin RN, MPA 5 , Elizabeth Molsen …
, research organizations, and industry from North America and Europe were invited to join the …

Functional status is frequently discussed as a key element of nursing practice and a critical
outcome criterion, and yet this phenomenon is poorly understood. Many important questions …