Damage of the airway epithelium and bronchial reactivity in patients with asthma

LA Laitinen, M Heino, A Laitinen, T Kava… - American Review of …, 1985 - atsjournals.org
… 40, with a constant air flow of 10 L/min. The output of the nebulizer used was found to be 0.57
ml … Laitinen LA. Histamine and methacholine challenge in the testing of bronchial reactivity. …

Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection

DW Empey, LA Laitinen, L Jacobs… - American Review of …, 1976 - atsjournals.org
Inhalation of histamine diphosphate aerosol (1.6 per cent, 10 breaths) produced a 218 ±
54.6 per cent (mean ± SE) increase in airway resistance in 16 normal subjects with colds …

Leksell's posteroventral pallidotomy in the treatment of Parkinson's disease

LV Laitinen, AT Bergenheim, MI Hariz - Journal of neurosurgery, 1992 - thejns.org
… We have also shown that L-dopa-induced choreoathetosis can be abolished by
stereotactic lesions in this part of the pallidum. The classical pallidotomy lesions placed …

[HTML][HTML] Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking

RA Pauwels, CG Löfdahl, LA Laitinen… - … England Journal of …, 1999 - Mass Medical Soc
Background and Methods Although patients with chronic obstructive pulmonary disease (COPD)
should stop smoking, some do not. In a double-blind, placebo-controlled study, we …

Asthma programme in Finland: a community problem needs community solutions

…, T Klaukka, K Koskela, M Erhola, LA Laitinen - Thorax, 2001 - thorax.bmj.com
Finland, like many other western countries, has experienced profound structural changes
during the post-war period: urbanisation, increasing education, smaller family size, improved …

[HTML][HTML] Comparison of a β2-Agonist, Terbutaline, with an Inhaled Corticosteroid, Budesonide, in Newly Detected Asthma

…, T Svahn, R Tammivaara, LA Laitinen - … England Journal of …, 1991 - Mass Medical Soc
Background. The presence of airway inflammation even in mild asthma points to the potential
value of antiinflammatory therapy. We compared the effect of an inhaled corticosteroid, …

[HTML][HTML] Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma

…, T Svahn, R Tammivaara, LA Laitinen - … England Journal of …, 1994 - Mass Medical Soc
Background In a previous study, we found that two years of treatment with an inhaled
corticosteroid, budesonide, was more effective than treatment with an inhaled β 2 -agonist, …

A comparative study of the effects of an inhaled corticosteroid, budesonide, and a β2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a …

LA Laitinen, A Laitinen, T Haahtela - Journal of allergy and clinical …, 1992 - Elsevier
L~ The mean age of the patients was 42 years (range, 21 to 59 years), mean height. 164 cm
(… Laitinen A. Ultrastructural organization of intraepithelial nerves in the human airway tract. …

Validity and repeatability of the IUATLD (1984) Bronchial Symptoms Questionnaire: an international comparison

PG Burney, LA Laitinen, S Perdrizet… - European respiratory …, 1989 - Eur Respiratory Soc
… with hyperresponsiveness in Germany and in the three continental counlries taken together,
and tightness in the chest or cough in the presence of animals, dust or feathers wa'l signifi…

Airway mucosal inflammation even in patients with newly diagnosed asthma

LA Laitinen, A Laitinen, T Haahtela - American Review of …, 1993 - atsjournals.org
We have studied bronchial biopsies from 14 patients with newly diagnosed asthma (four men
and 10 women), who had had asthma symptoms, on average, 7.4 months (range, 2 to 12 …