Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes

…, GG Brusselle, R Buhl, AA Cruz, L Duijts… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually
updated evidence-based strategy for asthma management and prevention, which can be …

[HTML][HTML] Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update

…, AA Cruz, JM Drazen, L Duijts, L Fleming… - NPJ primary care …, 2023 - nature.com
The Global Initiative for Asthma (GINA) was established in 1993 by the World Health
Organization and the US National Heart Lung and Blood Institute to improve asthma awareness, …

[HTML][HTML] Dietary inflammatory index and non-communicable disease risk: a narrative review

…, LW Chen, B Heude, JY Bernard, NC Harvey, L Duijts… - Nutrients, 2019 - mdpi.com
There are over 1,000,000 publications on diet and health and over 480,000 references on
inflammation in the National Library of Medicine database. In addition, there have now been …

Large-scale association analyses identify host factors influencing human gut microbiome composition

…, K Croitoru, GE Davies, CM van Duijn, L Duijts… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …

[PDF][PDF] DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis

…, C Ruiz, S Ligthart, T Wang, JA Taylor, L Duijts… - The American Journal of …, 2016 - cell.com
Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

…, VWV Jaddoe, A Simpson, JW Holloway, L Duijts… - Nature …, 2014 - nature.com
Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome-wide …

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

…, C Gieger, EG Burchard, NG Martin, L Duijts… - Nature …, 2015 - nature.com
Genetic association studies have identified 21 loci associated with atopic dermatitis risk
predominantly in populations of European ancestry. To identify further susceptibility loci for this …

Prolonged and exclusive breastfeeding reduces the risk of infectious diseases in infancy

L Duijts, VWV Jaddoe, A Hofman, HA Moll - Pediatrics, 2010 - publications.aap.org
OBJECTIVE: To examine the associations of duration of exclusive breastfeeding with infections
in the upper respiratory (URTI), lower respiratory (LRTI), and gastrointestinal tracts (GI) in …

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

…, BE Del-Rio-Navarro, KM Donohue, L Duijts… - Nature …, 2018 - nature.com
We examined common variation in asthma risk by conducting a meta-analysis of worldwide
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …

[HTML][HTML] The Generation R Study: design and cohort update 2017

…, CJ Kruithof, CM van Duijn, L Duijts… - European journal of …, 2016 - Springer
The Generation R Study is a population-based prospective cohort study from fetal life until
adulthood. The study is designed to identify early environmental and genetic causes and …