Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes
…, GG Brusselle, R Buhl, AA Cruz, L Duijts… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually
updated evidence-based strategy for asthma management and prevention, which can be …
updated evidence-based strategy for asthma management and prevention, which can be …
[HTML][HTML] Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update
The Global Initiative for Asthma (GINA) was established in 1993 by the World Health
Organization and the US National Heart Lung and Blood Institute to improve asthma awareness, …
Organization and the US National Heart Lung and Blood Institute to improve asthma awareness, …
[HTML][HTML] Dietary inflammatory index and non-communicable disease risk: a narrative review
There are over 1,000,000 publications on diet and health and over 480,000 references on
inflammation in the National Library of Medicine database. In addition, there have now been …
inflammation in the National Library of Medicine database. In addition, there have now been …
Large-scale association analyses identify host factors influencing human gut microbiome composition
…, K Croitoru, GE Davies, CM van Duijn, L Duijts… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …
[PDF][PDF] DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
environmental impacts on human disease. Maternal smoking in pregnancy remains an …
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
…, VWV Jaddoe, A Simpson, JW Holloway, L Duijts… - Nature …, 2014 - nature.com
Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome-wide …
childhood, but the underlying mechanisms are poorly understood. We performed a genome-wide …
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
Genetic association studies have identified 21 loci associated with atopic dermatitis risk
predominantly in populations of European ancestry. To identify further susceptibility loci for this …
predominantly in populations of European ancestry. To identify further susceptibility loci for this …
Prolonged and exclusive breastfeeding reduces the risk of infectious diseases in infancy
L Duijts, VWV Jaddoe, A Hofman, HA Moll - Pediatrics, 2010 - publications.aap.org
OBJECTIVE: To examine the associations of duration of exclusive breastfeeding with infections
in the upper respiratory (URTI), lower respiratory (LRTI), and gastrointestinal tracts (GI) in …
in the upper respiratory (URTI), lower respiratory (LRTI), and gastrointestinal tracts (GI) in …
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
…, BE Del-Rio-Navarro, KM Donohue, L Duijts… - Nature …, 2018 - nature.com
We examined common variation in asthma risk by conducting a meta-analysis of worldwide
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …
[HTML][HTML] The Generation R Study: design and cohort update 2017
…, CJ Kruithof, CM van Duijn, L Duijts… - European journal of …, 2016 - Springer
The Generation R Study is a population-based prospective cohort study from fetal life until
adulthood. The study is designed to identify early environmental and genetic causes and …
adulthood. The study is designed to identify early environmental and genetic causes and …