Background A variety of systemic diseases and conditions can affect the course of periodontitis
or have a negative impact on the periodontal attachment apparatus. Gingival recessions …

Oral conditions such as gingivitis and chronic periodontitis are found worldwide and are
among the most prevalent microbial diseases of mankind. The cause of these common …

… ( m V ), I s y n is synaptic input current ( p A ), G K represents conductance of K + ion, E K
represents reversal potential of K + ion, G N a represents conductance of Na + ion, E N a …

Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

… 3% n20 at 673 K, were analyzed using diffuse reflectance FT-IR (Japan Spectroscopic).
The amount of NOx stored at 623 K was measured using TG (Shimazu). The simulated gases …

Japanese mortality due to colorectal cancer is on the rise, surpassing 49,000 in 2015. Many
new treatment methods have been developed during recent decades. The Japanese …

Background Early clinical trials conducted primarily in Japan have shown that TAS-102, an
oral agent that combines trifluridine and tipiracil hydrochloride, was effective in the treatment …

… Ramucirumab is a fully human IgG-1 monoclonal antibody that binds with high affinity (K D
50 pmol/L) to the VEGFR-2 extracellular domain, which prevents binding of all VEGF ligands …

Purpose: B7-H1/PD-L1 (B7-H1) and B7-DC/PD-L2 (B7-DC) are ligands for the receptor PD-1,
which is known to negatively regulate T-cell activation. In the present study, we …