Background Smoking activates and recruits inflammatory cells and proteases to the airways.
Matrix metalloproteinase (MMP)-12 may be a key mediator in smoke induced emphysema. …

Recent studies have shown that cigarette smokers have diminished cough reflex sensitivity
compared with nonsmokers. The current authors proposed a mechanism of chronic cigarette …

Background. Chronic airway inflammation is most important pathological finding in asthma.
Cigarette smoking may modify type of inflammation as well as may influence disease severity …

Previous studies have shown that healthy cigarette smokers have diminished cough reflex
sensitivity compared to healthy nonsmokers. We have recently demonstrated that cough …

… A total of 20 runs were carried out for each K and the rate of change in the log probability of
the data between successive likelihood values (Δ K) was estimated using a 10 5 steps burn-…

Objective. The aim of study was to investigate a chemotactic effect of induced sputum and
bronchoalveolar lavage fluid on blood neutrophils in patients with chronic obstructive …

Background Proteomic studies of respiratory disorders have the potential to identify protein
biomarkers for diagnosis and disease monitoring. Utilisation of sensitive quantitative …

Cough reflex sensitivity has not been studied extensively in patients with chronic obstructive
pulmonary disease (COPD). The aim of the study was to evaluate cough reflex sensitivity to …

The perception of dyspnea varies widely among asthmatics and it is influenced by many
factors. The aims of our study were to investigate the perception of dyspnea during …

The hypothesis was that asthmatics might experience impaired perception of dyspnea and
salbutamol-induced reversibility during unlimited airway narrowing. A total of 38 asthmatics (…