Study of the reaction

…, W Kollmann, M Richardson, K Strauch, K Wacker… - Physical Review D, 1982 - APS
The Crystal Ball detector at SPEAR has been used to investigate the decays ψ′→ γ γ J ψ, J
ψ→(e+ e− or μ+ μ−) resulting from production of 8× 10 5 ψ′. From this selection of the data …

Systematic identification of trans eQTLs as putative drivers of known disease associations

…, M Roden, H Grallert, T Meitinger, K Strauch… - Nature …, 2013 - nature.com
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

…, A Peters, N Sattar, A Stančáková, K Strauch… - Nature …, 2018 - nature.com
We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130
European-descent individuals (9% cases), after imputation to high-density reference panels. …

BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF

…, P Schneider, ID Sizing, C Mullen, K Strauch… - Science, 2001 - science.org
B cell homeostasis has been shown to critically depend on BAFF, the B cell activation factor
from the tumor necrosis factor (TNF) family. Although BAFF is already known to bind two …

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

…, PE Slagboom, P Soininen, L Stolk, K Strauch… - Nature, 2017 - nature.com
Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at
risk of developing type 2 diabetes, cardiovascular disease and related metabolic and …

Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3–Internal Tandem Duplication Mutation …

…, A Neubauer, M Brugger, K Strauch… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Despite undergoing allogeneic hematopoietic stem cell transplantation (HCT),
patients with acute myeloid leukemia (AML) with internal tandem duplication mutation in the …

[HTML][HTML] Tobacco smoking leads to extensive genome-wide changes in DNA methylation

…, S Weidinger, E Lattka, J Adamski, A Peters, K Strauch… - PloS one, 2013 - journals.plos.org
Environmental factors such as tobacco smoking may have long-lasting effects on DNA
methylation patterns, which might lead to changes in gene expression and in a broader context to …

[HTML][HTML] Connecting genetic risk to disease end points through the human blood plasma proteome

…, EK Al-Dous, YA Mohamoud, J Malek, K Strauch… - Nature …, 2017 - nature.com
Genome-wide association studies (GWAS) with intermediate phenotypes, like changes in
metabolite and protein levels, provide functional evidence to map disease associations and …

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

…, E Trabetti, R Sorice, A Döring, E Lattka, K Strauch… - Nature …, 2013 - nature.com
Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory
arthritis. By combining data from >140,000 individuals of European ancestry within the Global …

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

…, N Novak, H Schulz, S Karrasch, C Gieger, K Strauch… - Nature …, 2017 - nature.com
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals 1 , partly because of a shared genetic origin 2 , 3 , 4 . To identify shared risk …