User profiles for K. Bracke

Ken Bracke

Ghent University
Verified email at UGent.be
Cited by 10186

New insights into the immunology of chronic obstructive pulmonary disease

GG Brusselle, GF Joos, KR Bracke - The Lancet, 2011 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated
with abnormal inflammatory immune responses of the lung to noxious particles and gases. …

[HTML][HTML] Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema

IK Demedts, T Demoor, KR Bracke, GF Joos… - Respiratory …, 2006 - Springer
Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation of
the airways and progressive destruction of lung parenchyma, a process that in most cases is …

Matrix metalloproteinases in asthma and COPD

IK Demedts, GG Brusselle, KR Bracke… - Current opinion in …, 2005 - Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are both highly prevalent,
chronic inflammatory lung diseases that lead to significant morbidity and mortality. Matrix …

Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease

IK Demedts, KR Bracke, G Van Pottelberge… - American journal of …, 2007 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway
inflammation. It is unclear if dendritic cells (DC) participate in this inflammatory process. …

Eosinophils in the spotlight: eosinophilic airway inflammation in nonallergic asthma

GG Brusselle, T Maes, KR Bracke - Nature medicine, 2013 - nature.com
BETWEEN BEDSIDE AND BENCH differentiation of naive T lymphocytes toward TH2 cells,
which produce cytokines such as interleukin-4 (IL-4), IL-5, IL-9 and IL-13 (ref. 2). Allergic TH2-…

Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice

KR Bracke, AI D'hulst, T Maes… - The Journal of …, 2006 - journals.aai.org
Chronic obstructive pulmonary disease (COPD) is mainly caused by cigarette smoking, and
is characterized by an increase in inflammatory cells in the airways and pulmonary tissue. …

Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD

NS Pauwels, KR Bracke, LL Dupont… - European …, 2011 - Eur Respiratory Soc
… KR Bracke and T. Vanden Berghe are postdoctoral researchers funded by FWO
Vlaanderen, and GR Van Pottelberge is a doctoral researcher funded by FWO Vlaanderen. …

MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease

GRV Pottelberge, P Mestdagh, KR Bracke… - American journal of …, 2011 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by progressive
inflammation in the airways and lungs combined with disturbed homeostatic functions of …

The RNA Atlas expands the catalog of human non-coding RNAs

…, N Nijs, T Taghon, K Vermaelen, KR Bracke… - Nature …, 2021 - nature.com
Existing compendia of non-coding RNA (ncRNA) are incomplete, in part because they are
derived almost exclusively from small and polyadenylated RNAs. Here we present a more …

Asthma inflammatory phenotypes show differential microRNA expression in sputum

…, V Sorbello, M Henket, K De Preter, KR Bracke… - Journal of Allergy and …, 2016 - Elsevier
Background Asthma is classified according to severity and inflammatory phenotype and is
likely to be distinguished by specific microRNA (miRNA) expression profiles. Objective We …