User profiles for K. Beagley

Kenneth Beagley

Professor of Immunology, Faculty of Health, Queensland University of Technology
Verified email at qut.edu.au
Cited by 14759

Immunological decision‐making: how does the immune system decide to mount a helper T‐cell response?

GE Kaiko, JC Horvat, KW Beagley, PM Hansbro - Immunology, 2008 - Wiley Online Library
Aberrant T‐cell responses underpin a range of diseases, including asthma and allergy and
autoimmune diseases. Pivotal immune elements of these diseases are the development of …

Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone

KW Beagley, CM Gockel - FEMS Immunology & Medical …, 2003 - academic.oup.com
Women mount more vigorous antibody- and cell-mediated immune responses following
either infection or vaccination than men. The incidence of most autoimmune diseases is also …

Male genital tract chlamydial infection: implications for pathology and infertility

KA Cunningham, KW Beagley - Biology of reproduction, 2008 - academic.oup.com
Chlamydia trachomatis infections are prevalent worldwide, but current research, screening,
and treatment are focused on females, with the burden of disease and infertility sequelae …

Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice

LA Dieleman, BU Ridwan, GS Tennyson, KW Beagley… - Gastroenterology, 1994 - Elsevier
Background/Aims: Oral administration of dextran sulfate sodium (DSS) has been reported to
induce colitis in mice. The purpose of this study was to determine whether the possible …

Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells.

KW Beagley, JH Eldridge, F Lee, H Kiyono… - The Journal of …, 1989 - rupress.org
Freshly isolated murine PP B cells were cultured with 10 different cytokines, including IL-1
alpha, IL-2, IL-4, IL-5, IL-6, IL-7, IFN-gamma, TNF-alpha, and TGF-beta, to investigate a …

Toll‐like receptor (TLR) expression and TLR‐mediated cytokine/chemokine production by human uterine epithelial cells

TM Schaefer, K Desouza, JV Fahey, KW Beagley… - …, 2004 - Wiley Online Library
The objective of this study was to examine the expression of toll‐like receptors (TLRs) by
the uterine epithelial cell line ECC‐1 and to determine if stimulation of the expressed TLRs …

Hapten-induced model of murine inflammatory bowel disease: mucosa immune responses and protection by tolerance.

…, KW Beagley, AT Sharmanov, K Fujihashi… - … (Baltimore, Md.: 1950 …, 1996 - journals.aai.org
We report here a murine model for experimental chronic colitis where administration of
trinitrobenzene sulfonic acid (TNBS) in 50% ethanol induced inflammation of large intestine in …

Interferon‐γ plays a critical role in intestinal immunity against Salmonella typhimurium infection

S Bao, KW Beagley, MP France, J Shen… - …, 2000 - Wiley Online Library
Salmonella bacteria are a major cause of food‐borne infectious diarrhoea and there is great
interest in understanding the pathogenesis of Salmonella infection and in vaccine …

Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine.

KW Beagley, K Fujihashi, AS Lagoo… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
Intraepithelial lymphocytes (IELs) have been extensively studied in the murine small intestine.
However, to date no studies have assessed IEL in the large intestine, despite the marked …

Neonatal chlamydial infection induces mixed T-cell responses that drive allergic airway disease

JC Horvat, KW Beagley, MA Wade… - American journal of …, 2007 - atsjournals.org
Rationale: Chlamydial lung infection has been associated with asthma in children and adults.
However, how chlamydial infection influences the development of immune responses that …