Background Asthma is associated with enormous healthcare expenditures that include both
direct and indirect costs. It is also associated with the loss of future potential earnings related …

Context Right heart catheterisation is the gold standard for the diagnosis of pulmonary
hypertension. However, echocardiography is frequently used to screen for this disease and …

PURPOSE: The aim of this study was to systematically review the literature on the effect of
statins on mortality in patients with infection and/or sepsis. MATERIALS AND METHODS: …

Epidemiological studies report an association between exposure to biomass smoke and
cardiopulmonary morbidity. The mechanisms for this association are unclear. The aim of the …

Background The 3-hydroxy 3-methylglutaryl coenzyme A reductase inhibitors (ie, statins)
are widely used for the treatment of patients with hypercholesterolemia and cardiovascular …

RATIONALE: There is a lack of consensus on factors that predict mortality in idiopathic pulmonary
arterial hypertension (IPAH). Tests that can accurately predict prognosis are needed to …

… Financial/nonfinancial disclosures: The authors have reported to CHEST the following
conflicts of interest: Dr Swiston has received honoraria for speaking engagements from Actelion …

Background The evolution in pulmonary arterial hypertension (PAH) management has been
summarised in three iterations of the European Society of Cardiology/European Respiratory …

BACKGROUND: Pulmonary embolism is a common condition. Some patients subsequently
develop chronic thromboembolic pulmonary hypertension (CTEPH). Many care gaps exist in …

Background Previous meta-analyses of treatments for pulmonary arterial hypertension (PAH)
have not shown mortality benefit from any individual class of medication. Methods …