[HTML][HTML] Bench-to-bedside review: acute respiratory distress syndrome–how neutrophils migrate into the lung
J Reutershan, K Ley - Critical care, 2004 - Springer
Acute lung injury and its more severe form, acute respiratory distress syndrome, are major
challenges in critically ill patients. Activation of circulating neutrophils and transmigration into …
challenges in critically ill patients. Activation of circulating neutrophils and transmigration into …
Leucocyte-endothelial interactions in health and disease
K Ley, J Reutershan - The vascular endothelium II, 2006 - Springer
The emigration of leucocytes into the tissue as a crucial step in the response to inflammatory
signals has been acknowledged for more than 100 years. The endothelium does not only …
signals has been acknowledged for more than 100 years. The endothelium does not only …
[HTML][HTML] CXCR2 in acute lung injury
FM Konrad, J Reutershan - Mediators of inflammation, 2012 - hindawi.com
In pulmonary inflammation, recruitment of circulating polymorphonuclear leukocytes is essential
for host defense and initiates the following specific immune response. One pathological …
for host defense and initiates the following specific immune response. One pathological …
Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury
J Reutershan, A Basit, EV Galkina… - American Journal of …, 2005 - journals.physiology.org
Infiltration of activated neutrophils [polymorphonuclear leukocytes (PMN)] into the lung is an
important component of the inflammatory response in acute lung injury. The signals required …
important component of the inflammatory response in acute lung injury. The signals required …
[HTML][HTML] Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung
J Reutershan, MA Morris, TL Burcin… - The Journal of …, 2006 - Am Soc Clin Investig
… This study was supported by the Deutsche Forschungsgemeinschaft (grant RE 1683/2-1;
to J. Reutershan) and by NIH grant HL73361 (to K. Ley and J. Linden). …
to J. Reutershan) and by NIH grant HL73361 (to K. Ley and J. Linden). …
[HTML][HTML] Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury
…, AL Vergis, J Reutershan, HP Cathro, J Linden… - Kidney international, 2009 - Elsevier
During renal ischemia-reperfusion, local and distant tissue injury is caused by an influx of
neutrophils into the affected tissues. Here we measured the kinetics of margination and …
neutrophils into the affected tissues. Here we measured the kinetics of margination and …
Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS‐induced PMN trafficking into the lungs
J Reutershan, I Vollmer, S Stark, R Wagner… - The FASEB …, 2009 - Wiley Online Library
Extracellular adenosine has been implicated as anti‐inflammatory signaling molecule
during acute lung injury (ALI). The main source of extracellular adenosine stems from a …
during acute lung injury (ALI). The main source of extracellular adenosine stems from a …
Protective effects of isoflurane pretreatment in endotoxin-induced lung injury
J Reutershan, D Chang, JK Hayes… - The Journal of the …, 2006 - pubs.asahq.org
Background The concept of antiinflammatory effects of volatile anesthetics is well established
in vitro and in some organ systems. Their protective role in lung injury, however, remains to …
in vitro and in some organ systems. Their protective role in lung injury, however, remains to …
ICAM-1 and LFA-1 play critical roles in LPS-induced neutrophil recruitment into the alveolar space
A Basit, J Reutershan, MA Morris… - … of Physiology-Lung …, 2006 - journals.physiology.org
Neutrophil recruitment into lung constitutes a major response to airborne endotoxins. In many
tissues endothelial intercellular adhesion molecule-1 (ICAM-1) interacts with lymphocyte …
tissues endothelial intercellular adhesion molecule-1 (ICAM-1) interacts with lymphocyte …
Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury
J Reutershan, RE Cagnina, D Chang… - The Journal of …, 2007 - journals.aai.org
To determine the role of the adenosine receptor A2a in a murine model of LPS-induced lung
injury, migration of polymorphonuclear leukocytes (PMNs) into the different compartments …
injury, migration of polymorphonuclear leukocytes (PMNs) into the different compartments …