Asthma phenotypes have been developed to address the complexities of the disease.
However, owing to a lack of longitudinal studies, little is known about the onset as well as the …

The house dust mite (HDM) is a major perennial allergen source and a significant cause of
allergic rhinitis and allergic asthma. However, awareness of the condition remains generally …

The delivery of drugs by inhalation is an integral component of asthma and chronic
obstructive pulmonary disease (COPD) management. However, even with effective inhaled …

Brain-derived neurotrophic factor (BDNF) is a key mediator of neuronal plasticity in the adult.
BDNF is known to be stored in human platelets and to circulate in plasma, but the …

Activation of lymphocyte subpopulations was determined in conjunction with levels of cytokines
in peripheral blood and bronchoalveolar lavage (BAL) of asthmatics. Allergic asthmatics …

Extracellular ATP serves as a danger signal to alert the immune system of tissue damage by
acting on P2X or P2Y receptors. Here we show that allergen challenge causes acute …

Background: The perceptions of patients and physicians regarding the symptoms and
impact of allergic rhinitis (AR) were assessed in a prospective, cross‐sectional, international …

… Author Contributions: Professor Virchow had full access to all of the data in the study and
takes responsibility for the integrity of the data and the accuracy of the data analysis. …

Although deposition of uric acid (UA) crystals is known as the cause of gout, it is unclear
whether UA plays a role in other inflammatory diseases. We here have shown that UA is …

Recommendations in asthma guidelines presuppose that practitioners have the evidence,
information, knowledge, and tools to select inhaler devices appropriate for individual patients. …