Background Several prediction models assessing future risk of exacerbations in adult patients
with asthma have been published. Applicability of these models is uncertain because their …

… Lapperre and Snoeck-Stroband contributed equally to the study and the manuscript. Drs.
Postma and Sterk also contributed equally to the study, the study supervision, and the …

Background: Chronic obstructive pulmonary disease (COPD) is associated with airway
inflammation. Although smoking cessation improves symptoms and the decline in lung function in …

Background: The importance of regular physical activity for patients with chronic obstructive
pulmonary disease (COPD) is well-established. However, many patients do not meet the …

Background Macrophages have been implicated in the pathogenesis of COPD. M1 and M2
macrophages constitute subpopulations displaying pro- and anti-inflammatory properties. …

Background Preventing exacerbations of asthma is a major goal in current guidelines. We
aimed to develop a prediction model enabling practitioners to identify patients at risk of severe …

Chronic obstructive pulmonary disease (COPD) is defined by progressive, irreversible airflow
limitation and an inflammatory response of the lungs, usually to cigarette smoke. However, …

Background Aiming at partly controlled asthma (PCa) instead of controlled asthma (Ca) might
decrease asthma medication use. Biomarkers, such as the fraction of exhaled nitric oxide (…

Mobile healthcare (mHealth) has the potential to revolutionise the self-management of long-term
medical conditions such as asthma. A user-centred design is integral if mHealth is to be …

The presence of chronic bronchitis predicts a more rapid decline of forced expiratory volume
in one second (FEV 1 ) in patients with chronic obstructive pulmonary disease (COPD). The …