Life after corpse engulfment: phagocytosis of apoptotic cells leads to VEGF secretion and cell growth

HA Golpon, VA Fadok… - The FASEB …, 2004 - Wiley Online Library
h. Since VEGF protein baseline levels were hardly detectable by ELISA we extended the
incubation time to 24 h… apoptotic cells for a period of 5 h before removing the apoptotic cells and …

miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer

S Zhong, H Golpon, P Zardo, J Borlak - Translational Research, 2021 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related death worldwide and miRNAs play
a key role in LC development. To better diagnose LC and to predict drug treatment …

Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy

…, RJ Barst, S Shapiro, H Golpon… - American journal of …, 2010 - atsjournals.org
Rationale: Pulmonary arterial hypertension (PAH) is a progressive condition with a poor
prognosis. Platelet-derived growth factor receptor (PDGFR) signaling plays an important role in …

Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension

MM Hoeper, C Faulenbach, H Golpon… - European …, 2004 - Eur Respiratory Soc
It has been proposed that targeted treatments should be combined for patients with idiopathic
pulmonary arterial hypertension (IPAH) responding insufficiently to monotherapy. This …

The prognostic impact of follow-up assessments in patients with idiopathic pulmonary arterial hypertension

N Nickel, H Golpon, M Greer, L Knudsen… - European …, 2012 - Eur Respiratory Soc
… The date of the first post-baseline catheterisation was defined as first follow-up and all
other assessments relevant for this study were performed within 24 h of the right heart …

Peroxisome proliferator-activated receptor gamma (PPARγ) expression is decreased in pulmonary hypertension and affects endothelial cell growth

S Ameshima, H Golpon, CD Cool, D Chan… - Circulation …, 2003 - Am Heart Assoc
… A vascular lesion from a patient with PH and Eisenmenger physiology is shown in G and
H. Lack of PPARγ staining is shown in G and lack of staining for active caspase 3 in H. A …

Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension

ME Yeager, GR Halley, HA Golpon, NF Voelkel… - Circulation …, 2001 - Am Heart Assoc
Golpon … The β-actin product melting temperature was 88C (continuous line), whereas
no characteristic melting peak was noted for H 2 O (no template control, dashed line). …

Preferences of lung cancer patients for treatment and decision‐making: a systematic literature review

…, K Damm, A Prenzler, H Golpon… - European journal of …, 2016 - Wiley Online Library
The consideration of patient preferences in decision‐making has become more important,
especially for life‐threatening diseases such as lung cancer. This paper aims to identify the …

Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis

…, T Gesell, ME Yeager, L Alger, H Golpon… - Circulation …, 2001 - Am Heart Assoc
Primary pulmonary hypertension (PPH) is a disease of unknown etiology characterized by
lumen-obliterating endothelial cell proliferation and vascular smooth muscle hypertrophy of …

Prognostic value of blood gas analyses in patients with idiopathic pulmonary arterial hypertension

MM Hoeper, MW Pletz, H Golpon… - European Respiratory …, 2007 - Eur Respiratory Soc
Blood gas abnormalities in patients with idiopathic pulmonary arterial hypertension (IPAH)
may be related to disease severity and prognosis. The present authors performed a 12-yr …