In non-small cell lung cancer, epidermal growth factor receptor gene mutations and anaplastic
lymphoma kinase (ALK) gene rearrangements have a major impact upon the level of …

… g–h Aberrant immunostaining of ROS1 in a transbronchial biopsy with lung adenocarcinoma.
g H&E stain, asterisks show tumour cells. h ROS1 IHC in adjacent hyperplastic type II …

… Endobronchial ultrasound (EBUS) with transbronchial needle aspiration using a 21–22 G
needle has a diagnostic yield of at least 90% in enlarged or bulky lymph nodes. Oesophageal …

Background Triple-negative breast cancer (TNBC) lacking expression of steroid receptors
and human epidermal growth factor receptor 2, having chemotherapy as the only therapeutic …

Napsin A is an aspartic proteinase expressed in lung and kidney. We have reported that
napsin A is expressed in type II pneumocytes and in adenocarcinomas of the lung. The …

This retrospective study investigates the correlation of intra-individual HER2 status between
primary breast cancers and corresponding recurrences in a population derived cohort. The …

High-grade transformation of acinic cell carcinoma (AciCC)(previously referred to as
dedifferentiation) is a rare phenomenon characterized by histologic progression of low-grade AciCC …

We present a series of 23 cases of a distinctive, hitherto poorly recognized low-grade
adenocarcinoma, with several histologic features reminiscent of papillary carcinoma of the thyroid, …

Background: Human papillomavirus (HPV) in tonsillar carcinoma is correlated with favourable
clinical outcome. Here, p16 INK4A , in situ HPV DNA hybridisation (ISH) and HPV L1 …

Introduction Detection of anaplastic lymphoma kinase (ALK)-gene rearrangements in non–small-cell
lung cancer (NSCLC) is mainly performed by fluorescence in-situ hybridization (…