Purpose Hypovitaminosis D is a highly spread condition correlated with increased risk of
respiratory tract infections. Nowadays, the world is in the grip of the Coronavirus disease 19 (…

Breath tests cover the fraction of nitric oxide in expired gas (F ENO ), volatile organic compounds
(VOCs), variables in exhaled breath condensate (EBC) and other measurements. For …

Severe asthma affects about 10% of the population with asthma and is characterized by low
lung function and a high count of blood leukocytes, mainly eosinophils. Various definitions …

Study objectives Obstructive sleep apnea (OSA) is characterized by recurrent apnea during
sleep that may compromise oxidative balance. Oxidative stress is increased in the blood and …

Introduction Research in the field of noninvasive ventilation (NIV) has contributed to the
development of new NIV interfaces. However, interface tolerance plays a crucial role in …

… Carpagnano MD a , Sergei A. Kharitonov MD, PhD b , Onofrio Resta MD, FCCP a , Maria P.
… Carpagnano, without whose dedicated and expert technical assistance this study would not …

According to the data derived from several national and international registries, including SANI
(Severe Asthma Network Italy), and considering the strong impact that frequent or regular …

Background Clinicians are increasingly recognizing severe asthma patients in whom biologics
and other add-on therapies lead to dramatic improvement. Currently, there is no agreed-…

Background: Hyperoxia increases oxidative stress through the generation of reactive oxygen
species and may therefore enhance inflammation in the lungs. The aim of this study was to …

Cigarette smoking induces an inflammatory response in the airways that may play a key
role in the pathogenesis of chronic obstructive pulmonary disease. Noninvasive markers of …