… Neptune and an associated magnetosphere and magnetic tail. The detached bow shock
wave in the supersonic solar wind flow was detected upstream at 34.9 Neptune … of Neptune by …

Aortic aneurysm and dissection are manifestations of Marfan syndrome (MFS), a disorder
caused by mutations in the gene that encodes fibrillin-1. Selected manifestations of MFS reflect …

We report heterozygous mutations in the genes encoding either type I or type II transforming
growth factor β receptor in ten families with a newly described human phenotype that …

Marfan syndrome is an autosomal dominant disorder of connective tissue caused by
mutations in fibrillin-1 (encoded by FBN1 in humans and Fbn1 in mice), a matrix component of …

Many chemoattractants cause chemotaxis of leukocytes by stimulating a structurally distinct
class of G protein-coupled receptors. To identify receptor functions required for chemotaxis, …

Persistent directional movement of neutrophils in shallow chemotactic gradients raises the
possibility that cells can increase their sensitivity to the chemotactic signal at the front, relative …

Pertussis toxin inhibits chemotaxis of neutrophils by preventing chemoattractant receptors
from activating trimeric G proteins in the G i subfamily. In HEK293 cells expressing …

E-cigarette or vaping product use–associated lung injury (EVALI) is a severe pulmonary
illness associated with the use of e-cigarettes or vaping products that was officially identified …

Only a fraction of all smokers develop chronic obstructive pulmonary disease (COPD),
suggesting a large role for genetic susceptibility. The leptin receptor (LEPR) is present in human …

Accelerated lung function decline is a key COPD phenotype; however, its genetic control
remains largely unknown. We performed a genome-wide association study using the Illumina …