Effects of flavonoids on the release of reactive oxygen species by stimulated human neutrophils: Multivariate analysis of structure-activity relationships (SAR)
B Limasset, C Le Doucen, JC Dore, T Ojasoo… - Biochemical …, 1993 - Elsevier
… principal chemical modifications concern the C ring in our population of molecules; C&
unsaturation, a keto group at C4 and a hydroxyl group at C, which can be glycosylated as in …
unsaturation, a keto group at C4 and a hydroxyl group at C, which can be glycosylated as in …
Wine phenolic antioxidants inhibit AP-1 transcriptional activity
…, JP Cristol, S Delbosc, C Le Doucen… - Journal of Agricultural …, 2001 - ACS Publications
Some of the beneficial effects of moderate wine consumption may be related to the antioxidant
properties of polyphenolic compounds containing tannins, flavonoids, and phenolic acids. …
properties of polyphenolic compounds containing tannins, flavonoids, and phenolic acids. …
Increased oxygen species generation in blood monocytes of asthmatic patients
I Vachier, M Damon, C Le Doucen… - American Review of …, 1992 - atsjournals.org
… Cells were then incubated in petri dishes with 2 ml RPMI 1640medium and 20% fetal calf
serum for 2 h at 37 C in a humid atmosphere of 95070 air and 5% CO2 , The monolayers …
serum for 2 h at 37 C in a humid atmosphere of 95070 air and 5% CO2 , The monolayers …
Enhancement of reactive oxygen species formation in stable and unstable asthmatic patients
There is increasing evidence to suggest that human blood polymorphonuclear neutrophils (PMNs)
and monocytes play an important role in the inflammatory processes of asthma. In …
and monocytes play an important role in the inflammatory processes of asthma. In …
Antioxidant activity of micronized diosmin on oxygen species from stimulated human neutrophils
B Cypriani, B Limasset, ML Carrie, C Le Doucen… - Biochemical …, 1993 - Elsevier
… c by SOD-sensitive agents was determined after addition of SOD (3Opg). Ferricytochrome
c … The results represent means C SEM of triplicate determinations in three experiments. …
c … The results represent means C SEM of triplicate determinations in three experiments. …
Cellular protein kinase C activity in asthma.
…, T Radeau, C Le Doucen, C Leger… - American journal of …, 1997 - atsjournals.org
Protein kinase C (PKC) is a primary group of enzymes mediating signal transduction for a
wide variety of functions in many different cell types. Its activation has been implicated in …
wide variety of functions in many different cell types. Its activation has been implicated in …
Reciprocal effects between opioid peptides and human polymorphonuclear leukocytes—II: Enhancement of phorbol myristate acetate-induced respiratory burst in …
A Slaoui-Hasnaoui, MC Guerin, C Le Doucen… - Biochemical …, 1992 - Elsevier
Activated oxygen species (AOS) have often been shown to promote strong modifications in
peptide structures and thus in their biological functions. In the present study, the …
peptide structures and thus in their biological functions. In the present study, the …
Affinity chromatography at sub-zero temperatures: A model study with porcine pancreatic elastase
C Balny, C Le Doucen, P Douzou, JG Bieth - Journal of Chromatography A, 1979 - Elsevier
… The specificity was checked with ovalbumin, cytochrome c, trypsin and c-chymotrypsin
under conditions identical with those used for elastase. With ovalbumin and cytochrome c, the …
under conditions identical with those used for elastase. With ovalbumin and cytochrome c, the …
Temperature dependence of the absorption in the region beyond the 4.3-μm band head of CO2. 2: N2 and O2 broadening
In this paper we present the first accurate determination, from laboratory measurements, of
the temperature dependence of CO_2 continuous absorption beyond the ν_3 band head, …
the temperature dependence of CO_2 continuous absorption beyond the ν_3 band head, …
Imaging reactive oxygen species in asthma
I Vachier, CL Doucen, J Loubatière… - Journal of …, 1994 - Wiley Online Library
… These first observations were obtained with conventional methods such as ferricytochrome
c assays to detec superoxide anions and scopoletin assays to detect hydrogen peroxide. …
c assays to detec superoxide anions and scopoletin assays to detect hydrogen peroxide. …