Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent
exacerbations in many patients. There have been no previous international guidelines. The …

Background Increasing numbers of individuals with cystic fibrosis are becoming infected with
the multidrug-resistant non-tuberculous mycobacterium (NTM) Mycobacterium abscessus, …

Lung infections with Mycobacterium abscessus, a species of multidrug-resistant nontuberculous
mycobacteria, are emerging as an important global threat to individuals with cystic …

Background Since the publication of the British Thoracic Society (BTS) Guideline on the ‘Management
of opportunistic mycobacterial infections’ in 2000, our understanding of the …

Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause
chronic pulmonary infection, particularly in individuals with pre-existing inflammatory lung …

Cystic fibrosis (CF) is the most common genetic disease within the Caucasian population and
leads to premature respiratory failure. Approximately 60,000 individuals are currently living …

CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary ciliary …

There is a need for a clear definition of exacerbations used in clinical trials in patients with
bronchiectasis. An expert conference was convened to develop a consensus definition of an …

Azithromycin is a potent macrolide antibiotic with poorly understood antiinflammatory properties.
Long-term use of azithromycin in patients with chronic inflammatory lung diseases, such …

Rationale: Chronic infection with Pseudomonas aeruginosa is associated with an increased
exacerbation frequency, a more rapid decline in lung function, and increased mortality in …