[HTML][HTML] The role of fluoroquinolones in the treatment of tuberculosis in 2019

AD Pranger, TS Van Der Werf, JGW Kosterink… - Drugs, 2019 - Springer
The inability to use powerful antituberculosis drugs in an increasing number of patients seems
to be the biggest threat towards global tuberculosis (TB) elimination. Simplified, shorter …

[HTML][HTML] Pharmacokinetic drug interactions of antimicrobial drugs: a systematic review on oxazolidinones, rifamycines, macrolides, fluoroquinolones, and beta-lactams

MS Bolhuis, PN Panday, AD Pranger, JGW Kosterink… - Pharmaceutics, 2011 - mdpi.com
Like any other drug, antimicrobial drugs are prone to pharmacokinetic drug interactions.
These drug interactions are a major concern in clinical practice as they may have an effect on …

Evaluation of moxifloxacin for the treatment of tuberculosis: 3 years of experience

AD Pranger, R Van Altena… - European …, 2011 - Eur Respiratory Soc
Moxifloxacin (MFX) is a powerful second-line anti-tuberculosis (TB) agent, but the optimal
dose has not yet been established and long-term safety data are scarce. We retrospectively …

Effect of spaceflight on human stem cell hematopoiesis: suppression of erythropoiesis and myelopoiesis

…, C Serke, T Delaplaine, A Pranger… - Journal of leukocyte …, 1996 - academic.oup.com
Humans subjected to periods of microgravity develop anemia, thrombocytopenia, and
abnormalities in red blood cell structure. The causes of these abnormalities are complex and …

[HTML][HTML] T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

…, NJ Kloosterhuis, R Havinga, AT Pranger… - Nature …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease driven by hypercholesterolemia. During
aging, T cells accumulate cholesterol, potentially affecting inflammation. However, the effect of …

Evaluation of co-trimoxazole in the treatment of multidrug-resistant tuberculosis

N Alsaad, R van Altena, AD Pranger… - European …, 2013 - Eur Respiratory Soc
Co-trimoxazole (SXT), a combination of sulfamethoxazole and trimethoprim, has shown in
vitro activity against Mycobacterium tuberculosis. However, the pharmacokinetic and …

Determination of moxifloxacin in human plasma, plasma ultrafiltrate, and cerebrospinal fluid by a rapid and simple liquid chromatography-tandem mass spectrometry …

AD Pranger, JWC Alffenaar, A Mireille… - Journal of analytical …, 2010 - academic.oup.com
Moxifloxacin (MFX) is a useful agent in the treatment of multi-drug-resistant tuberculosis (MDR-TB).
At Tuberculosis Centre Beatrixoord, a referral center for tuberculosis in the …

Limited-sampling strategies for therapeutic drug monitoring of moxifloxacin in patients with tuberculosis

AD Pranger, JGW Kosterink, R van Altena… - Therapeutic drug …, 2011 - journals.lww.com
Background: Moxifloxacin (MFX) is a potent drug for multidrug resistant tuberculosis (TB)
treatment and is also useful if first-line agents are not tolerated. Therapeutic drug monitoring …

Determination of reference intervals for urinary steroid profiling using a newly validated GC-MS/MS method

WHA de Jong, E Buitenwerf, AT Pranger… - Clinical Chemistry and …, 2017 - degruyter.com
Background: Urinary steroid profiling (USP) is a powerful diagnostic tool to asses disorders
of steroidogenesis. Pre-analytical factors such as age, sex and use of oral contraceptive pills (…

[HTML][HTML] Dynamics of maternal androgens and its metabolites during early embryonic development: embryonic modification of a maternal effect

…, B Riedstra, M van Faassen, A Pranger… - Journal of …, 2023 - joe.bioscientifica.com
In birds, exposure to maternal (yolk) testosterone affects a diversity of offspring post-hatching
traits, which eventually affect offspring competitiveness. However, maternal testosterone is …