BACKGROUND: Children infected with Mycobacterium tuberculosis have significant risk of
developing tuberculosis (TB) and can therefore benefit from preventive therapy.OBJECTIVE: …

Background Microbiological confirmation of childhood tuberculosis is rare because of the
difficulty of collection of specimens, low sensitivity of smear microscopy, and poor access to …

Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Consensus case definitions for childhood tuberculosis have been proposed by an international
expert panel, aiming to standardize the reporting of cases in research focusing on the …

Tuberculosis control relies on the identification and preventive treatment of individuals who
are latently infected with Mycobacterium tuberculosis. However, direct identification of latent …

Xpert ® MTB/RIF offers new and important possibilities for the diagnosis of sputum smear-negative
tuberculosis (TB) and/or rifampicin (RMP) resistance, and many are encouraging …

Background . Diagnosis of childhood tuberculosis (TB) is challenging. The widely used
tuberculin skin test (TST) may produce -positive results because of cross-reactivity with …

The introduction of new rapid diagnostic tools for tuberculosis (TB) and the promising TB drugs
pipeline together with the development of a new World Health Organization Strategy post …

Tuberculosis commonly affects young children (< 5 years) in countries that have high rates
of child mortality. 1 The global public health focus to control tuberculosis has traditionally …

Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization (WHO)‐…