Positive effects of acute and moderate physical exercise on cognitive function

…, T Maruyama, M Murota, Y Nakahara - Journal of physiological …, 2009 - jstage.jst.go.jp
Some researchers have reported that moderate physical exercise improves cognitive function,
and that exercise at high intensity beyond the optimal point attenuates performance, in an …

Hair analysis for abused and therapeutic drugs

Y Nakahara - Journal of Chromatography B: Biomedical Sciences …, 1999 - Elsevier
This review focuses on basic aspects and recent studies of hair analysis for abused and
therapeutic drugs and is discussed with 164 references. Firstly, biology of hair and sampling of …

Establishment of a Rearing System of the Extremotolerant Tardigrade Ramazzottius varieornatus: A New Model Animal for Astrobiology

…, T Kunieda, W Abe, M Watanabe, Y Nakahara… - Astrobiology, 2008 - liebertpub.com
Studies on the ability of multicellular organisms to tolerate specific environmental extremes
are relatively rare compared to those of unicellular microorganisms in extreme environments. …

Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled …

…, YH Kim, S Kuyama, T Maeda, M Morise, Y Nakahara… - The Lancet, 2019 - thelancet.com
Background Most patients with small-cell lung cancer (SCLC) have extensive-stage disease
at presentation, and prognosis remains poor. Recently, immunotherapy has demonstrated …

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

…, K Nakamura, M Matsui, A Yamamoto, Y Nakahara… - Nature, 2006 - nature.com
Autophagy is an intracellular bulk degradation process through which a portion of the
cytoplasm is delivered to lysosomes to be degraded 1 , 2 , 3 , 4 . Although the primary role of …

Durvalumab, with or without tremelimumab, plus platinum–etoposide versus platinum–etoposide alone in first-line treatment of extensive-stage small-cell lung cancer …

…, T Maeda, T Kawamura, Y Nakahara… - The Lancet …, 2021 - thelancet.com
Background First-line durvalumab plus etoposide with either cisplatin or carboplatin (platinum–etoposide)
showed a significant improvement in overall survival versus platinum–…

The mouse homolog of Drosophila Vasa is required for the development of male germ cells

…, R Akasu, Y Katoh-Fukui, Y Nakahara… - Genes & …, 2000 - genesdev.cshlp.org
Restricted expression of a mouse Vasa homolog gene (Mvh) expression is first detected in
primordial germ cells (PGCs) after colonization of the genital ridges. Subsequently,Mvh is …

Maximum entropy analysis of the spectral functions in lattice QCD

M Asakawa, Y Nakahara, T Hatsuda - Progress in Particle and Nuclear …, 2001 - Elsevier
First principle calculation of the QCD spectral functions (SPFs) based on the lattice QCD
simulations is reviewed. Special emphasis is placed on the Bayesian inference theory and the …

Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled …

…, T Kato, M Ichiki, H Saka, K Hirano, Y Nakahara… - The Lancet …, 2019 - thelancet.com
Background Dual blockade of the EGFR and VEGF pathways in EGFR-mutated metastatic
non-small-cell lung cancer (NSCLC) is supported by preclinical and clinical data, yet the …

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison… - Nature …, 2009 - nature.com
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the
genomes of 212 medulloblastomas, malignant pediatric brain tumors. We found focal …