… Liu S, Zhu Y, Chen W, Wang L, Zhang X, Zhang Y. Demographic and Socioeconomic Factors
Influencing the Incidence of Ankle … Yoshiyuki Kizawa MD, PhD … Yoshiyuki Kizawa MD, PhD …

Rationale: Patients with chronic obstructive pulmonary disease (COPD) show a poor response
to corticosteroids. This has been linked to a reduction of histone deacetylase-2 as a result …

… Tatsuya Morita, Tatsuo Akechi, Masayuki Ikenaga, Yoshiyuki Kizawa, Hiroyuki Kohara,
Taketo Mukaiyama, Toshimichi Nakaho, Nobuaki Nakashima, Yasuo Shima, Tatsuhiro …

Despite the advancement of modern medicine, cancer remains one of the leading causes of
death across the globe. 1 Patients with cancer may react to diagnostic, prognostic, and …

Although palliative sedation therapy is often required in terminally ill cancer patients, its
efficacy and safety are not sufficiently understood. The primary aims of this multicenter …

Background Communication about the ending of anticancer treatment and transition to palliative
care is a difficult task for oncologists. The primary aims of this study were to clarify family-…

Palliative care in Japan has progressed rapidly, and the Cancer Control Act has played a
very important role in developing palliative medicine. Challenges include developing a …

Background Although alleviation of existential distress is important for terminally ill cancer
patients, the concept of existential distress has not been fully understood. The aim of this study …

Context Few studies have explored the clinical significance of the family's presence or absence
at the moment of a patient's death and meaningful communication (saying “goodbye”) in …

Objective: The aim of this project was to develop an appropriate and valid instrument for
assessment by medical professionals in Japanese palliative care settings.Methods: We …