… In a study published after the 2007 review, Wedzicha and colleagues (30) noted a statistically
significant improvement among symptomatic patients with severe airflow obstruction (…

Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in
death, usually from respiratory failure, within 2-3 years of symptom onset. Non-invasive …

Objectives To evaluate the efficacy of hospital at home schemes compared with inpatient
care in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). …

Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …

This guideline is an official statement of the American College of Physicians (ACP), American
College of Chest Physicians (ACCP), American Thoracic Society (ATS), and European …

Objectives: To determine the effectiveness of non-invasive positive pressure ventilation (NPPV)
in the management of respiratory failure secondary to acute exacerbation of chronic …

Rationale: Frequent chronic obstructive pulmonary disease (COPD) exacerbations are a
major cause of hospital admission and mortality and are associated with increased airway …

BACKGROUND Methods of classifying chronic obstructive pulmonary disease (COPD)
depend largely upon spirometric measurements but disability is only weakly related to …

Although exacerbations of chronic obstructive pulmonary disease (COPD) are associated
with symptomatic and physiological deterioration, little is known of the time course and …

Non-invasive ventilation has been used in chronic respiratory failure due to chronic
obstructive pulmonary disease (COPD), but the effect of the addition of nasal positive-pressure …