Aberrant microRNA (miRNA) expression is a defining feature of human malignancy. Specific
miRNAs have been identified as promoters or suppressors of metastatic progression. …

Big Data and artificial intelligence will have a profound transformational impact on governments
around the world. Thus, it is important for scholars to provide a useful analysis on the …

There are a number of specific characteristics in the system parasites–zoos and lots of
studies in this connection have been carried out. In the present work a literature review of the …

Through in vivo selection of human cancer cell populations, we uncover a convergent and
cooperative miRNA network that drives melanoma metastasis. We identify miR-1908, miR-…

We develop multiscale mortar mixed finite element discretizations for second order elliptic
equations. The continuity of flux is imposed via a mortar finite element space on a coarse grid …

Hybrid materials based on polyvinylpyrrolidone (PVP) with silver nanoparticles (AgNps)
were synthesized applying two different strategies based on thermal or chemical reduction of …

BRAF(V600E) mutant melanomas treated with inhibitors of the BRAF and MEK kinases
almost invariably develop resistance that is frequently caused by reactivation of the mitogen …

Intratumor heterogeneity is a key factor contributing to therapeutic failure and, hence,
cancer lethality. Heterogeneous tumors show partial therapy responses, allowing for the …

Melanoma metastasis is a devastating outcome lacking an effective preventative therapeutic.
We provide pharmacologic, molecular, and genetic evidence establishing the liver-X …

Novel hybrid material thin films based on polyvinyl alcohol (PVA)/tetraethyl orthosilicate (TEOS)
with embedded silver nanoparticles (AgNps) were synthesized using sol–gel method. …