Polymeric antitumor agents on a molecular and on a cellular level?
L Gros, H Ringsdorf, H Schupp - … Chemie International Edition …, 1981 - Wiley Online Library
“Chemistry has become a mature science, with all the advantages and handicaps of maturity:
harvest is abundant, but many people think future and adventure are to be found elsewhere…
harvest is abundant, but many people think future and adventure are to be found elsewhere…
Enzymology of the repair of free radicals-induced DNA damage
L Gros, MK Saparbaev, J Laval - Oncogene, 2002 - nature.com
A number of intrinsic and extrinsic mutagens induce structural damage in cellular DNA. These
DNA damages are cytotoxic, miscoding or both and are believed to be at the origin of cell …
DNA damages are cytotoxic, miscoding or both and are believed to be at the origin of cell …
Understanding, improving and using green fluorescent proteins
…, R Heim, SR Adams, AE Boyd, LA Gross… - Trends in biochemical …, 1995 - cell.com
… Boyd and L Gross, unpublished). The proposed mechanism predicts a loss of 2~ whereas
cyclization after oxidation would give a 20Da loss. Measured time constants for the oxidative …
cyclization after oxidation would give a 20Da loss. Measured time constants for the oxidative …
Association of β2‐adrenergic receptor polymorphisms with severe asthma
…, Sawyer, Fitzharris, Pearce, L Gros… - Clinical & …, 2000 - Wiley Online Library
Background There is considerable interest in the role of different candidate loci in the
development of asthma. This study investigates the association between asthma severity and …
development of asthma. This study investigates the association between asthma severity and …
“Spontaneous” Leukemia Developing in G3H Mice Following Inoculation, In Infancy, with AK-Emkemic.
L Gross - Proceedings of the Society for Experimental …, 1951 - journals.sagepub.com
Seven of 14 C3H mice inoculated when less than 12 hours old with Ak leukemic extracts
developed leukemia at 8 to 11 months of age. 2. Four of 6 C3H mice inoculated. when less than …
developed leukemia at 8 to 11 months of age. 2. Four of 6 C3H mice inoculated. when less than …
[HTML][HTML] Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT
…, M Ciufolini, L Gros, M Humbert, N Castéran, L Borge… - PloS one, 2009 - journals.plos.org
Background The stem cell factor receptor, KIT, is a target for the treatment of cancer,
mastocytosis, and inflammatory diseases. Here, we characterise the in vitro and in vivo profiles of …
mastocytosis, and inflammatory diseases. Here, we characterise the in vitro and in vivo profiles of …
[PDF][PDF] Blocking antibodies targeting the CD39/CD73 immunosuppressive pathway unleash immune responses in combination cancer therapies
…, M Giraudon-Paoli, S Augier, A Docquier, L Gros… - Cell reports, 2019 - cell.com
Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers
are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting …
are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting …
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective …
…, F Guilhot, F Huguet, F Nicolini, L Legros… - The lancet …, 2010 - thelancet.com
Background Imatinib treatment significantly improves survival in patients with chronic myeloid
leukaemia (CML), but little is known about whether treatment can safely be discontinued in …
leukaemia (CML), but little is known about whether treatment can safely be discontinued in …
Living with television: The violence profile
G Gerbner, L Gross - The Fear of Crime, 2017 - taylorfrancis.com
… Douglass Cater and Stephen Strickland wrote a book on the report and argued for “ongoing
research capable of undergirding large public policy investigations” (l,p.l33). And, finally, a …
research capable of undergirding large public policy investigations” (l,p.l33). And, finally, a …
The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway
In nucleotide incision repair (NIR), an endonuclease nicks oxidatively damaged DNA in a
DNA glycosylase‐independent manner, providing the correct ends for DNA synthesis coupled …
DNA glycosylase‐independent manner, providing the correct ends for DNA synthesis coupled …