Newborn screening and diagnosis of mucopolysaccharidoses
…, T Fujii, M Fukushi, T Oguma, T Shimada… - Molecular genetics and …, 2013 - Elsevier
… In 2007, Oguma and Tomatsu developed a highly sensitive, specific, accurate, and inexpensive
strategy in which DS, HS, and KS disaccharides are produced from GAGs in blood and …
strategy in which DS, HS, and KS disaccharides are produced from GAGs in blood and …
Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers
…, M Tachibana, H Masumoto, T Oguma… - The Journal of …, 2010 - Wiley Online Library
… AUC 0-t and AUC 0-t were calculated by the trapezoidal method to the last time point. AUC
0-∞ was estimated by addition of extrapolation using the last plasma concentration/Λ, added …
0-∞ was estimated by addition of extrapolation using the last plasma concentration/Λ, added …
Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids
…, T Nagasaki, I Ito, T Oguma, H Inoue, T Tajiri… - Journal of allergy and …, 2013 - Elsevier
… of eosinophils, mast cells, and T H 2 cells with several mediators and T H 2 cytokines,
such as … Therefore, we hypothesized that periostin would be a novel biomarker of T H 2/eosinophil-…
such as … Therefore, we hypothesized that periostin would be a novel biomarker of T H 2/eosinophil-…
Enantioenriched Synthesis of C1-Symmetric BINOLs: Iron-Catalyzed Cross-Coupling of 2-Naphthols and Some Mechanistic Insight
…, T Oguma, T Kunisu, T Katsuki - Journal of the …, 2010 - ACS Publications
Highly enantioselective aerobic oxidative cross-coupling of 2-naphthols with broad substrate
scope was achieved using an iron(salan) complex as the catalyst. Enantiomeric excesses …
scope was achieved using an iron(salan) complex as the catalyst. Enantiomeric excesses …
Role of prostaglandin D2 and its receptors in the pathophysiology of asthma
T Oguma, K Asano, A Ishizaka - Allergology International, 2008 - jstage.jst.go.jp
… Sequencing of the DP gene revealed three variants (T-549C, C-441T, and T-197C) in the 5’…
-Americans, carriers of the C allele of T-549C, or of the T allele of C-441T, were at higher risk …
-Americans, carriers of the C allele of T-549C, or of the T allele of C-441T, were at higher risk …
[HTML][HTML] New clinical diagnostic criteria for allergic bronchopulmonary aspergillosis/mycosis and its validation
…, K Kamei, M Taniguchi, T Shimoda, T Oguma… - Journal of Allergy and …, 2021 - Elsevier
Background There are several clinical diagnostic criteria for allergic bronchopulmonary
aspergillosis (ABPA). However, these criteria have not been validated in detail, and no criteria …
aspergillosis (ABPA). However, these criteria have not been validated in detail, and no criteria …
[HTML][HTML] Role of prostanoid DP receptor variants in susceptibility to asthma
Background Previous genetic studies have associated the region of the human genome (14q22.1)
containing the gene for the prostanoid DP receptor (PTGDR) with asthma. A study of a …
containing the gene for the prostanoid DP receptor (PTGDR) with asthma. A study of a …
Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans
MS Bathala, H Masumoto, T Oguma, L He… - Drug Metabolism and …, 2012 - ASPET
This study determined the mass balance and pharmacokinetics of edoxaban in humans after
oral administration of [ 14 C]edoxaban. After oral administration of 60 mg (as active moiety) …
oral administration of [ 14 C]edoxaban. After oral administration of 60 mg (as active moiety) …
Impact of exacerbations on emphysema progression in chronic obstructive pulmonary disease
N Tanabe, S Muro, T Hirai, T Oguma… - American journal of …, 2011 - atsjournals.org
Rationale: Low-attenuation areas assessed by computed tomography reflect the extent of
pathological emphysema and correlate with airflow limitation and mortality in patients with …
pathological emphysema and correlate with airflow limitation and mortality in patients with …
Population pharmacokinetics of vancomycin in Japanese adult patients
…, T Iga, H Zenda, K Okumura, T Oguma… - Therapeutic drug …, 1998 - journals.lww.com
Population pharmacokinetic parameters of vancomycin (VCM) in Japanese adult patients
infected with methicillin-resistant Staphylococcus aureus (MRSA) were estimated using 1253 …
infected with methicillin-resistant Staphylococcus aureus (MRSA) were estimated using 1253 …