Newborn screening and diagnosis of mucopolysaccharidoses

…, T Fujii, M Fukushi, T Oguma, T Shimada… - Molecular genetics and …, 2013 - Elsevier
… In 2007, Oguma and Tomatsu developed a highly sensitive, specific, accurate, and inexpensive
strategy in which DS, HS, and KS disaccharides are produced from GAGs in blood and …

Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers

…, M Tachibana, H Masumoto, T Oguma… - The Journal of …, 2010 - Wiley Online Library
… AUC 0-t and AUC 0-t were calculated by the trapezoidal method to the last time point. AUC
0-∞ was estimated by addition of extrapolation using the last plasma concentration/Λ, added …

Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids

…, T Nagasaki, I Ito, T Oguma, H Inoue, T Tajiri… - Journal of allergy and …, 2013 - Elsevier
… of eosinophils, mast cells, and T H 2 cells with several mediators and T H 2 cytokines,
such as … Therefore, we hypothesized that periostin would be a novel biomarker of T H 2/eosinophil-…

Enantioenriched Synthesis of C1-Symmetric BINOLs: Iron-Catalyzed Cross-Coupling of 2-Naphthols and Some Mechanistic Insight

…, T Oguma, T Kunisu, T Katsuki - Journal of the …, 2010 - ACS Publications
Highly enantioselective aerobic oxidative cross-coupling of 2-naphthols with broad substrate
scope was achieved using an iron(salan) complex as the catalyst. Enantiomeric excesses …

Role of prostaglandin D2 and its receptors in the pathophysiology of asthma

T Oguma, K Asano, A Ishizaka - Allergology International, 2008 - jstage.jst.go.jp
… Sequencing of the DP gene revealed three variants (T-549C, C-441T, and T-197C) in the 5’…
-Americans, carriers of the C allele of T-549C, or of the T allele of C-441T, were at higher risk …

[HTML][HTML] New clinical diagnostic criteria for allergic bronchopulmonary aspergillosis/mycosis and its validation

…, K Kamei, M Taniguchi, T Shimoda, T Oguma… - Journal of Allergy and …, 2021 - Elsevier
Background There are several clinical diagnostic criteria for allergic bronchopulmonary
aspergillosis (ABPA). However, these criteria have not been validated in detail, and no criteria …

[HTML][HTML] Role of prostanoid DP receptor variants in susceptibility to asthma

T Oguma, LJ Palmer, E Birben, LA Sonna… - … England Journal of …, 2004 - Mass Medical Soc
Background Previous genetic studies have associated the region of the human genome (14q22.1)
containing the gene for the prostanoid DP receptor (PTGDR) with asthma. A study of a …

Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans

MS Bathala, H Masumoto, T Oguma, L He… - Drug Metabolism and …, 2012 - ASPET
This study determined the mass balance and pharmacokinetics of edoxaban in humans after
oral administration of [ 14 C]edoxaban. After oral administration of 60 mg (as active moiety) …

Impact of exacerbations on emphysema progression in chronic obstructive pulmonary disease

N Tanabe, S Muro, T Hirai, T Oguma… - American journal of …, 2011 - atsjournals.org
Rationale: Low-attenuation areas assessed by computed tomography reflect the extent of
pathological emphysema and correlate with airflow limitation and mortality in patients with …

Population pharmacokinetics of vancomycin in Japanese adult patients

…, T Iga, H Zenda, K Okumura, T Oguma… - Therapeutic drug …, 1998 - journals.lww.com
Population pharmacokinetic parameters of vancomycin (VCM) in Japanese adult patients
infected with methicillin-resistant Staphylococcus aureus (MRSA) were estimated using 1253 …