User profiles for T. Nakashima

Tsutomu Nakashima

- Verified email at med.nagoya-u.ac.jp - Cited by 15077

Takuya Nakashima

- Verified email at omu.ac.jp - Cited by 7168

Tomoharu Nakashima

- Verified email at kis.osakafu-u.ac.jp - Cited by 5703

RANKL–RANK signaling in osteoclastogenesis and bone disease

T Wada, T Nakashima, N Hiroshi… - Trends in molecular …, 2006 - cell.com
Hundreds of millions of people worldwide are affected by bone-related diseases, such as
osteoporosis and rheumatoid arthritis. Understanding the molecular mechanisms of bone …

Osteoimmunology: the conceptual framework unifying the immune and skeletal systems

K Okamoto, T Nakashima, M Shinohara… - Physiological …, 2017 - journals.physiology.org
… We review the various osteoimmune pathologies, including the bone destruction in RA,
in which pathogenic helper T cell subsets [such as IL-17-expressing helper T (Th17) cells] …

JCS 2018 guideline on diagnosis and treatment of acute coronary syndrome

…, A Tanaka, T Tamura, T Nakashima, T Noguchi… - Circulation …, 2019 - jstage.jst.go.jp
Acute coronary syndromes (ACS) are a comprehensive disease concept characterized by
acute myocardial ischemia caused by disruption of coronary artery plaque and consequent …

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

T Nakashima, M Hayashi, T Fukunaga, K Kurata… - Nature medicine, 2011 - nature.com
… Despite T cell expression of RANKL, the osteoclastogenic T cell subset is limited to autoimmune
T cells 1 , and RANKL expression in bone marrow cells, including T cells, is much lower …

Regulation of cancer cell migration and bone metastasis by RANKL

DH Jones, T Nakashima, OH Sanchez, I Kozieradzki… - Nature, 2006 - nature.com
Bone metastases are a frequent complication of many cancers that result in severe disease
burden and pain 1 , 2 , 3 . Since the late nineteenth century, it has been thought that the …

Facile discrimination of aldose enantiomers by reversed-phase HPLC

T Tanaka, T Nakashima, T Ueda, K Tomii… - Chemical and …, 2007 - jstage.jst.go.jp
One-pot reactions of aldoses with L-cysteine methyl ester and o-tolyl isothiocyanate yielded
methyl 2-(polyhydroxyalkyl)-3-(o-tolylthiocarbamoyl)-thiazolidine-4 (R)-carboxylates. Direct …

Psychological effects of forest environments on healthy adults: Shinrin-yoku (forest-air bathing, walking) as a possible method of stress reduction

…, Y Iwai, T Nakashima, H Ohira, T Shirakawa - Public health, 2007 - Elsevier
OBJECTIVES: Shinrin-yoku (walking and/or staying in forests in order to promote health) is
a major form of relaxation in Japan; however, its effects have yet to be completely clarified. …

Pathology of hepatocellular carcinoma in Japan: 232 consecutive cases autopsied in ten years

T Nakashima, K Okuda, M Kojiro, A Jimi… - Cancer, 1983 - Wiley Online Library
… on growth pattern or a modification of Nakashima and Sakamoto’s classification3 was
employed. … Nakashima T. Vascular changes and hernodynamics in hepatocellular carcinoma. In: …

Performance evaluation of fuzzy classifier systems for multidimensional pattern classification problems

…, T Nakashima, T Murata - IEEE Transactions on …, 1999 - ieeexplore.ieee.org
We examine the performance of a fuzzy genetics-based machine learning method for
multidimensional pattern classification problems with continuous attributes. In our method, each …

Osteoprotection by semaphorin 3A

M Hayashi, T Nakashima, M Taniguchi, T Kodama… - Nature, 2012 - nature.com
… of the RANKL-induced inhibition of Nrp1 expression, we examined the involvement of the
transcription factors nuclear factor-κB (NF-κB), c-Fos and nuclear factor of activated T cells c1 (…