Background: Spirometry is the most common pulmonary function test. It is widely used in the
assessment of lung function to provide objective information used in the diagnosis of lung …

Background Appropriate interpretation of pulmonary function tests (PFTs) involves the
classification of observed values as within/outside the normal range based on a reference …

Recent genetic, structural and functional studies have identified the airway and lung epithelium
as a key orchestrator of the immune response. Further, there is now strong evidence that …

Background: Exercise-induced bronchoconstriction (EIB) describes acute airway narrowing
that occurs as a result of exercise. EIB occurs in a substantial proportion of patients with …

Background: The American Thoracic Society committee on Proficiency Standards for Pulmonary
Function Laboratories has recognized the need for a standardized reporting format for …

This international task force report updates general considerations for bronchial challenge
testing and the performance of the methacholine challenge test. There are notable changes …

Rationale: Exercise-induced bronchoconstriction (EIB) is a highly prevalent condition with
unclear pathogenesis. Two competing theories of the pathogenesis of EIB differ regarding the …

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive disease with a median
survival of ∼3 yrs. Measurements of airflow and lung volumes at rest are generally used to …

BACKGROUND: Asthma and obesity are common conditions that are strongly associated.
This association might be due to shared genetic or environmental causes. OBJECTIVE: We …

Leukotrienes are clearly involved in airway inflammation and certain clinical features of
asthma. Evolving evidence indicates that leukotriene B 4 has an important role in the …