… Considerable effort is expended to protect today’s children from lead exposure, but there
is little evidence on the harms past lead exposures continue to hold for yesterday’s children, …

The emergence and spread of parasite resistance to currently available antimalarials has
highlighted the importance of developing novel antimalarials. This scoping review provides an …

Background Female pattern hair loss (FPHL) is a common trait in which androgens and
oestrogens may have a pathogenic role. The aromatase enzyme converts androgens to …

… For instance, consider forced expiratory volume in 1 s … data on the outcome measure(s)
from the same individual at … obtained at prior time point(s), and this dependence needs to be …

Antimalarial drugs are vital for treating malaria and controlling transmission. Measuring drug
efficacy in the field requires large clinical trials and thus we have identified proxy measures …

Rationale: Better characterization of childhood wheeze phenotypes using newer statistical
methods provides a basis for addressing the heterogeneity of childhood asthma. Outcomes of …

Objective To define longitudinal childhood wheeze phenotypes and identify their early-life
risk factors. Study design Current wheeze was recorded 23 times up to age 7 years in a birth …

… E(a, t) is the combined killing effect of the drugs and has been modified from that presented
in Zaloumis et al. (17) to account for three drugs and accommodate drug interactions. The …

… Our results, in conjunction with Hillmer et al.’s findings, might rather suggest that the
polyglycine repeat is not functionally significant in AGA, but that it is in fact other variation in or …

Background SARS-CoV-2 booster vaccination should ideally enhance protection against
variants and minimise immune imprinting. This Phase I trial evaluated two vaccines targeting …