The heat-shock proteins
S Lindquist, EA Craig - Annual review of genetics, 1988 - annualreviews.org
… coli but is present in proteins of S. cerevisiae. There is no evidence that S. cerevisiae is
naturally … Thus, if this protein domain should serve the same function in S. cerevisiae that it is …
naturally … Thus, if this protein domain should serve the same function in S. cerevisiae that it is …
The heat-shock response
S Lindquist - Annual review of biochemistry, 1986 - annualreviews.org
… hsp70 is reported to be phosphorylated (125), but attempts to detect phosphorylation of the
chicken, mammalian, and Drosophila proteins have not been successful (126; S. Lindquist, …
chicken, mammalian, and Drosophila proteins have not been successful (126; S. Lindquist, …
HSP90 and the chaperoning of cancer
L Whitesell, SL Lindquist - Nature Reviews Cancer, 2005 - nature.com
… at present, but work is underway to better define the role(s) of HSP90 in cancer evolution. …
Rutherford, SL & Lindquist, S. Hsp90 as a capacitor for morphological evolution. Nature 396…
Rutherford, SL & Lindquist, S. Hsp90 as a capacitor for morphological evolution. Nature 396…
Hsp90 as a capacitor for morphological evolution
SL Rutherford, S Lindquist - Nature, 1998 - nature.com
The heat-shock protein Hsp90 supports diverse but specific signal transducers and lies at the
interface of several developmental pathways. We report here that when Drosophila Hsp90 …
interface of several developmental pathways. We report here that when Drosophila Hsp90 …
The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins
DA Parsell, S Lindquist - Annual review of genetics, 1993 - annualreviews.org
… Even here, tolerance is reduced only a few fold (J Taulien & S Lindquist, unpublished). Thus,
while the smhsps may play an important role in thermotolerance in mammalian cells, they …
while the smhsps may play an important role in thermotolerance in mammalian cells, they …
[HTML][HTML] First case of 2019 novel coronavirus in the United States
ML Holshue, C DeBolt, S Lindquist… - New England journal …, 2020 - Mass Medical Soc
An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread
rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV …
rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV …
α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
…, J LaBaer, JC Rochet, NM Bonini, S Lindquist - Science, 2006 - science.org
… We are grateful to members of the Lindquist lab for helpful suggestions and comments on
the manuscript, especially J. Shorter and B. Bevis for advice and encouragement and T. …
the manuscript, especially J. Shorter and B. Bevis for advice and encouragement and T. …
Li+ Ion Insertion in TiO2 (Anatase). 2. Voltammetry on Nanoporous Films
…, J Hjelm, A Hagfeldt, SE Lindquist - The Journal of …, 1997 - ACS Publications
… The diffusion coefficient at 25 C in the nanoporous structure was approximately 2 × 10 -17
cm 2 /s for insertion and 4 × 10 -17 cm 2 /s for extraction. The activation energy was 0.4 eV for …
cm 2 /s for insertion and 4 × 10 -17 cm 2 /s for extraction. The activation energy was 0.4 eV for …
Protein disaggregation mediated by heat-shock protein Hspl04
DA Parsell, AS Kowal, MA Singer, S Lindquist - Nature, 1994 - nature.com
THE heat-inducible members of the HsplOO (or Clp) family of proteins share a common function
in helping organisms to survive extreme stress, but the basic mechanism through which …
in helping organisms to survive extreme stress, but the basic mechanism through which …
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
… coli and S. cerevisiae, whereas almost all H. sapiens HSP90s are in an open conformation.
… coli and S. cerevisiae proteins with the non-hydrolysable ATP analogue AMPPNP drives …
… coli and S. cerevisiae proteins with the non-hydrolysable ATP analogue AMPPNP drives …