… Imashuku S, Hibi S, Todo S: Hemophagocytic lymphohistiocytosis in infancy and childhood.
… Matsumoto Y, Naniwa D, Banno S, et al: The efficacy of therapeutic plasmapheresis for the …

… Other continuation regimens for refractory cases were modeled on chemotherapy for
Hodgkin’s disease (HD) or non-Hodgkin’s lymphoma (NHL).37,38 Specific agents and their …

A prospective multicenter trial of 119 children 1 to 18 years of age with newly diagnosed
aplastic anemia (AA) was conducted, comparing treatment using antithymocyte globulin (ATG), …

Perforin gene (PRF1) mutations appear to occur in about 30% of patients with haemophagocytic
lymphohistiocytosis (HLH). We tested perforin expression and gene mutations in 14 …

Purpose: The study was performed to clarify in the hemophagocytic syndrome (HPS) how
cytokinemia plays a role in its pathogenesis and if cytokinemia is of prognostic value. Patients …

Most patients with acute myeloid leukemia (AML) enter complete remission (CR) after
treatment with chemotherapy, but a large number of them experience relapse with resistant …

Dysfunction of glutamatergic neurotransmission has been implicated in the pathogenesis of
epilepsy and numerous other neurological diseases. Here we describe the discovery of a …

… Imashuku S, Hibi S, Todo S, et al. Allogeneic hematopoietic stem cell transplantation for
patients with hemophagocytic syndrome (HPS) in Japan. Bone Marrow Transplant 1999;23:569–…

… I), is the first step in saving a patient’s life. To date, plasma exchange or blood exchange …
Experimental strategies using EBV-specific CTLs for Hodgkin’s disease and NPC may help …

The hemophagocytic lymphohistiocytoses (HLH) comprise a heterogeneous group of disorders
characterized by dysregulated activation of T cells and macrophages. Although some …