User profiles for S. Chhabra

Sandeep Chhabra

Amgen Inc
Verified email at amgen.com
Cited by 2001

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones

…, MK Winson, L Fish, A Taylor, SR Chhabra… - …, 1997 - microbiologyresearch.org
… enterocolitica and S. liquefaciens, bacteria we have previously shown to … Intriguingly, in the
S. liquefaciens extract, there is a third … library and may represent a novel S. liquefaciens AHL. …

Quinolones: from antibiotics to autoinducers

S Heeb, MP Fletcher, SR Chhabra… - FEMS microbiology …, 2011 - academic.oup.com
… Furthermore, long-term exposure of S. aureus to … Interestingly, the formation of S. aureus
small-colony variants … HHQ and PHQ have antibacterial activity against Vibrio anguillarum, S. …

[HTML][HTML] Tea and tea polyphenols in cancer prevention

CS Yang, JY Chung, G Yang, SK Chhabra… - The Journal of nutrition, 2000 - Elsevier
The inhibitory action of tea (Camellia sinensis) and tea components against cancer formation
has been demonstrated in different animal models involving different organ sites in many …

Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing

…, JP Throup, F Jørgensen, SR Chhabra… - FEMS microbiology …, 1998 - academic.oup.com
… These sensors can be used in a series of experiments to characterise the AHL signal(s)
involved in quorum sensing for a given organism. Simple T-streaks or assays of conditioned …

The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.

…, NJ Bainton, M Birdsall, BW Bycroft, SR Chhabra… - The EMBO …, 1993 - embopress.org
Erwinia carotovora and Pseudomonas aeruginosa secrete exoenzymes that contribute to
the pathogenesis of plant and mammalian infections respectively. E.carotovora mutants …

N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and …

…, C Buckley, S Atkinson, SR Chhabra… - Infection and …, 2002 - Am Soc Microbiol
… 2A), with the organism reaching final OD 600 s of 3.7 and 3.8, respectively. In MOPS-buffered
LB medium, the pH ranged from 6.7 to 7.6 over the growth curve compared with 7.16 to 8.5 …

The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density‐dependency of the quorum sensing hierarchy, regulates rhl‐dependent genes …

SP Diggle, K Winzer, SR Chhabra… - Molecular …, 2003 - Wiley Online Library
In Pseudomonas aeruginosa, diverse exoproduct virulence determinants are regulated via
N‐acylhomoserine lactone‐dependent quorum sensing. Here we show that 2‐heptyl‐3‐…

CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation

…, RW Jenkins, S Li, R Dries, K Yates, S Chhabra… - Cancer discovery, 2018 - AACR
Immune checkpoint blockade, exemplified by antibodies targeting the PD-1 receptor, can
induce durable tumor regressions in some patients. To enhance the efficacy of existing …

Allogeneic BCMA-targeting CAR T cells in relapsed/refractory multiple myeloma: phase 1 UNIVERSAL trial interim results

S Mailankody, JV Matous, S Chhabra, M Liedtke… - Nature medicine, 2023 - nature.com
… Springer Nature or its licensor (eg a society or other partner) holds exclusive rights to this
article under a publishing agreement with the author(s) or other rightsholder(s); author self-…

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

…, EL Seifert, SJ Hewitt, S Chhabra… - Human molecular …, 2010 - academic.oup.com
Growing evidence highlights a role for mitochondrial dysfunction and oxidative stress as
underlying contributors to Parkinson's disease (PD) pathogenesis. DJ-1 (PARK7) is a recently …