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Pathogenesis of immune thrombocytopenia

S Audia, M Mahévas, M Samson, B Godeau… - Autoimmunity …, 2017 - Elsevier
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to an abnormal T cell
response, notably supported by splenic T follicular helper cells, that stimulates the proliferation …

Recent advances in our understanding of giant cell arteritis pathogenesis

M Samson, M Corbera-Bellalta, S Audia… - Autoimmunity …, 2017 - Elsevier
… by DC that present still unidentified antigen(s). The presence of proinflammatory cytokines
(… microenvironment, which is impacted by GCA treatment(s) and/or the natural history of the …

[HTML][HTML] Evans' syndrome: from diagnosis to treatment

S Audia, N Grienay, M Mounier, M Michel… - Journal of Clinical …, 2020 - mdpi.com
Evans’ syndrome (ES) is defined as the concomitant or sequential association of warm auto-immune
haemolytic anaemia (AIHA) with immune thrombocytopenia (ITP), and less …

Further characterization of clinical and laboratory features in VEXAS syndrome: large‐scale analysis of a multicentre case series of 116 French patients

…, J Jeannel, A Servettaz, S Audia… - British Journal of …, 2022 - academic.oup.com
Background A new autoinflammatory syndrome related to somatic mutations of UBA1 was
recently described and called VEXAS syndrome (‘Vacuoles, E1 Enzyme, X‐linked, …

Brief report: inhibition of interleukin‐6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis

M Samson, S Audia, N Janikashvili… - Arthritis & …, 2012 - Wiley Online Library
Objective From an immunologic standpoint, the mechanisms by which treatment with
tocilizumab (TCZ), a humanized anti–interleukin‐6 (anti–IL‐6) receptor antibody, results in …

Alice: lessons learned from building a 3D system for novices

M Conway, S Audia, T Burnette, D Cosgrove… - Proceedings of the …, 2000 - dl.acm.org
We present lessons learned from developing Alice, a 3D graphics programming environment
designed for undergraduates with no 3D graphics or programming experience. Alice is a …

Different phenotypes in dermatomyositis associated with anti-MDA5 antibody: study of 121 cases

…, R Borie, C Deligny, B Terrier, A Berezne, S Audia… - Neurology, 2020 - AAN Enterprises
Objectives The predominance of extramuscular manifestations (eg, skin rash, arthralgia,
interstitial lung disease [ILD]) as well as the low frequency of muscle signs in anti–melanoma …

Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis

M Samson, S Audia, J Fraszczak, M Trad… - Arthritis & …, 2012 - Wiley Online Library
Objective Giant cell arteritis (GCA) is the most frequently occurring vasculitis in elderly
individuals, and its pathogenesis is not fully understood. The objective of this study was to …

Safety and efficacy of rituximab in adult immune thrombocytopenia: results from a prospective registry including 248 patients

…, J Graveleau, B Slama, S Audia… - Blood, The Journal …, 2014 - ashpublications.org
We conducted a prospective multicenter registry of 248 adult patients with immune
thrombocytopenia (ITP) treated with rituximab to assess safety. We also assessed response and …

The reversed halo sign: pathognomonic pattern of pulmonary mucormycosis in leukemic patients with neutropenia?

…, ML Chrétien, I Lafon, E Ferrant, S Audia… - Clinical infectious …, 2014 - academic.oup.com
Background. Pulmonary mucormycosis (PM) is a life-threatening fungal infection with an
increasing incidence among patients with acute leukemia. In some immunocompromised hosts, …
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