Chronic obstructive pulmonary disease (COPD) is a known risk factor for developing lung
cancer but the underlying mechanisms remain unknown. We hypothesise that the COPD …

Introduction Exacerbations are a leading cause of morbidity in COPD. The objective of this
study was to identify metabolomic biomarkers of acute exacerbations of COPD (AECOPD). …

Background Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disorder
associated with lung microbiome dysbiosis. Although the upper airway microbiome is the …

The lung microbiome is an inflammatory stimulus whose role in the development of lung
malignancies is incompletely understood. We hypothesized that the lung microbiome …

Cytochrome P450 enzymes are hemeproteins that catalyze the monooxygenation of a wide‐range
of structurally diverse substrates of endogenous and exogenous origin. These heme …

… Shane Hodgson: none. Kiat Ruxrungtham: protected research time was provided by the
Department of Medicine, The Faculty of Medicine, Chulalongkorn University, Thailand. Chris …

Background The lung microbiome is an inflammatory stimulus whose role in COPD pathogenesis
is incompletely understood. We hypothesised that the frequent exacerbator phenotype …

Concordant U-Pb dates of magmatic monazites in the dominant coarse-grained biotite (±muscovite)
granites of the late Variscan Cornubian batholith demonstrate that the emplacement …

Based on whole mtDNA sequencing of 14 samples from Northern Island Melanesia, we
characterize three formerly unresolved branches of macrohaplogroup M that we call …

U-Pb ages determined using sensitive high-resolution ion microprobe-reverse geometry on
205 single-grain zircons from 16 ash beds within submarine fan deposits of the Ecca Group …