Although advances in intensive care have enabled more patients to survive an acute critical
illness, they also have created a large and growing population of chronically critically ill …

Background Communication between families and providers in the ICU affects patient and
family outcomes and use of health-care resources. Recent research studies have tested …

Intensive care unit physicians frequently provide care to patients who survive initial life-threatening
events but are unable to recover rapidly to a point that they are fully independent of …

… Carson received grants from the NIH and the Biomarck Corporation. Ms. Harmon’s, Ms. …
Carson SS, Cox CE, Holmes GM, et al. The changing epidemiology of mechanical ventilation: a …

Context Studies suggest that many survivors of critical illness experience long-term cognitive
impairment but have not included premorbid measures of cognitive functioning and have …

Objective: To demonstrate the feasibility of a placebo-controlled trial of antipsychotics for
delirium in the intensive care unit and to test the hypothesis that antipsychotics would improve …

Background There are conflicting data on the effects of antipsychotic medications on delirium
in patients in the intensive care unit (ICU). Methods In a randomized, double-blind, placebo…

Background: Growing numbers of critically ill patients receive prolonged mechanical ventilation.
Little is known about the patterns of care as patients transition from acute care hospitals …

Objective. —To compare the effects of change from an open to a closed intensive care unit (ICU)
format on clinical outcomes, resource utilization, teaching, and perceptions regarding …

Objectives: The epidemiology of chronic critical illness is not well characterized. We sought
to determine the prevalence, outcomes, and associated costs of chronic critical illness in the …