BACKGROUND: There is increasing evidence that environmental exposures determining
childhood illnesses operate early in life. Prenatal exposure to a farming environment through …

… Further details can be found in Van Strien et al. (16). At 2 years of age, no relevant effects
of the intervention on atopic symptoms were noted (Koopman et al., 17), but at this young age, …

Background: Despite public concern about potential adverse health effects of concentrated
animal feeding operations, objectively assessed data on environmental exposure to …

BACKGROUND: Endotoxin exposure has been shown to be associated with a decreased
prevalence of atopic sensitization and symptoms. Yet endotoxin represents only a part of the …

BACKGROUND: Exposure to microbial agents might inhibit the development of atopy and
asthma. OBJECTIVE: We measured the association between microbial exposure assessed at …

Background: Epidemiologic studies have demonstrated an association between indoor
fungal growth and respiratory symptoms. However, in only a few studies was fungal exposure …

In 1990, a case-control study was conducted in the Netherlands into the association between
damp housing, childhood respiratory symptoms, and sensitization to house dust mites and …

BACKGROUND: The relationship between mite and pet allergen exposure in infancy and
the subsequent development of sensitization and asthma is complex. OBJECTIVE: We …

Objective. To investigate the association between contacts with other children and the
development of respiratory infections in the first year of life in children with or without genetic …

Background It has been suggested that the period immediately after birth is a sensitive
period for the development of atopic disease. Objective We investigated whether birth …