User profiles for R. Vehring
Reinhard VehringVerified email at ualberta.ca Cited by 6867 |
[HTML][HTML] Pharmaceutical Particle Engineering via Spray Drying
R Vehring - Pharmaceutical research, 2008 - Springer
This review covers recent developments in the area of particle engineering via spray drying.
The last decade has seen a shift from empirical formulation efforts to an engineering …
The last decade has seen a shift from empirical formulation efforts to an engineering …
Particle formation in spray drying
R Vehring, WR Foss, D Lechuga-Ballesteros - Journal of aerosol science, 2007 - Elsevier
… (7) Pe i = - r s ∂ r s D i ∂ t = κ 8 D i . For R = 1 we find the surface concentration(8) c s , i = c
m , i 3 β i exp Pe i 2 with β i = ∫ 0 1 R 2 exp Pe i 2 R 2 d R . β must be integrated numerically …
m , i 3 β i exp Pe i 2 with β i = ∫ 0 1 R 2 exp Pe i 2 R 2 d R . β must be integrated numerically …
Respirable bacteriophages for the treatment of bacterial lung infections
This review article discusses the development of respiratory therapeutics containing
bacteriophages indicated for lung infections, specifically those that have become increasingly …
bacteriophages indicated for lung infections, specifically those that have become increasingly …
Novel cosuspension metered-dose inhalers for the combination therapy of chronic obstructive pulmonary disease and asthma
D Lechuga-Ballesteros, B Noga, R Vehring… - Future medicinal …, 2011 - Future Science
Pressurized metered dose inhaler is the most common inhaled dosage form, ideally suited
for delivering the highly potent compounds that medicinal chemists typically discover for …
for delivering the highly potent compounds that medicinal chemists typically discover for …
Mechanistic models facilitate efficient development of leucine containing microparticles for pulmonary drug delivery
…, MA Gwin, PR Finlay, PJ Kuehl, R Vehring - International journal of …, 2011 - Elsevier
Mechanistic models of the spray drying and particle formation processes were used to conduct
a formulation study with minimal use of material and time. A model microparticle vehicle …
a formulation study with minimal use of material and time. A model microparticle vehicle …
Trileucine improves aerosol performance and stability of spray‐dried powders for inhalation
For particles to be useful medicinal aerosols, not only their aerodynamic diameter has to be
on the order of a few micrometers but also they have to be chemically and physically stable. …
on the order of a few micrometers but also they have to be chemically and physically stable. …
Spray-dried respirable powders containing bacteriophages for the treatment of pulmonary infections
Myoviridae bacteriophages were processed into a dry powder inhalable dosage form using
a low‐temperature spray‐drying process. The phages were incorporated into microparticles …
a low‐temperature spray‐drying process. The phages were incorporated into microparticles …
Production of inhalation phage powders using spray freeze drying and spray drying techniques for treatment of respiratory infections
Purpose The potential of aerosol phage therapy for treating lung infections has been
demonstrated in animal models and clinical studies. This work compared the performance of two …
demonstrated in animal models and clinical studies. This work compared the performance of two …
Improvement of the dispersibility of spray-dried budesonide powders using leucine in an ethanol–water cosolvent system
A new approach for enhancing the dispersibility of respirable powders containing poorly
soluble pharmaceutical actives is demonstrated. Budesonide was spray-dried with leucine from …
soluble pharmaceutical actives is demonstrated. Budesonide was spray-dried with leucine from …
Physical stability of salmon calcitonin spray-dried powders for inhalation
The effects of excipient crystallinity and water content on the physical stability of salmon
calcitonin (sCT) in a spray-dried powder for inhalation have been investigated. sCT was …
calcitonin (sCT) in a spray-dried powder for inhalation have been investigated. sCT was …