User profiles for R. Vehring

Reinhard Vehring

Verified email at ualberta.ca
Cited by 6867

[HTML][HTML] Pharmaceutical Particle Engineering via Spray Drying

R Vehring - Pharmaceutical research, 2008 - Springer
This review covers recent developments in the area of particle engineering via spray drying.
The last decade has seen a shift from empirical formulation efforts to an engineering …

Particle formation in spray drying

R Vehring, WR Foss, D Lechuga-Ballesteros - Journal of aerosol science, 2007 - Elsevier
… (7) Pe i = - r s ∂ r s D i ∂ t = κ 8 D i . For R = 1 we find the surface concentration(8) c s , i = c
m , i 3 β i exp Pe i 2 with β i = ∫ 0 1 R 2 exp Pe i 2 R 2 d R . β must be integrated numerically …

Respirable bacteriophages for the treatment of bacterial lung infections

…, WH Finlay, JJ Dennis, R Vehring - Journal of aerosol …, 2013 - liebertpub.com
This review article discusses the development of respiratory therapeutics containing
bacteriophages indicated for lung infections, specifically those that have become increasingly …

Novel cosuspension metered-dose inhalers for the combination therapy of chronic obstructive pulmonary disease and asthma

D Lechuga-Ballesteros, B Noga, R Vehring… - Future medicinal …, 2011 - Future Science
Pressurized metered dose inhaler is the most common inhaled dosage form, ideally suited
for delivering the highly potent compounds that medicinal chemists typically discover for …

Mechanistic models facilitate efficient development of leucine containing microparticles for pulmonary drug delivery

…, MA Gwin, PR Finlay, PJ Kuehl, R Vehring - International journal of …, 2011 - Elsevier
Mechanistic models of the spray drying and particle formation processes were used to conduct
a formulation study with minimal use of material and time. A model microparticle vehicle …

Trileucine improves aerosol performance and stability of spray‐dried powders for inhalation

…, CL Stevenson, DP Miller, R Vehring… - Journal of …, 2008 - Elsevier
For particles to be useful medicinal aerosols, not only their aerodynamic diameter has to be
on the order of a few micrometers but also they have to be chemically and physically stable. …

Spray-dried respirable powders containing bacteriophages for the treatment of pulmonary infections

…, KH Lynch, JJ Dennis, WH Finlay, R Vehring - Journal of …, 2011 - Elsevier
Myoviridae bacteriophages were processed into a dry powder inhalable dosage form using
a low‐temperature spray‐drying process. The phages were incorporated into microparticles …

Production of inhalation phage powders using spray freeze drying and spray drying techniques for treatment of respiratory infections

…, T Parumasivam, FG Gao, NB Carrigy, R Vehring… - Pharmaceutical …, 2016 - Springer
Purpose The potential of aerosol phage therapy for treating lung infections has been
demonstrated in animal models and clinical studies. This work compared the performance of two …

Improvement of the dispersibility of spray-dried budesonide powders using leucine in an ethanol–water cosolvent system

…, DP Miller, D Lechuga-Ballesteros, R Vehring - Powder technology, 2013 - Elsevier
A new approach for enhancing the dispersibility of respirable powders containing poorly
soluble pharmaceutical actives is demonstrated. Budesonide was spray-dried with leucine from …

Physical stability of salmon calcitonin spray-dried powders for inhalation

…, K Pikal-Cleland, DP Miller, R Vehring… - Journal of …, 2004 - Elsevier
The effects of excipient crystallinity and water content on the physical stability of salmon
calcitonin (sCT) in a spray-dried powder for inhalation have been investigated. sCT was …