Stimulation of soluble guanylate cyclase prevents cigarette smoke–induced pulmonary hypertension and emphysema

…, A Pichl, N Parajuli, M Seimetz, R Puig-Pey… - American journal of …, 2014 - atsjournals.org
… Raquel Puig-Pey … Raquel Puig-Pey … In addition, total pulmonary resistance and
intrapulmonary vessel muscularization were significantly related (P < 0.001; r = 0.59). …

[HTML][HTML] Cigarette smoke challenges bone marrow mesenchymal stem cell capacities in guinea pig

O Tura-Ceide, B Lobo, T Paul, R Puig-Pey… - Respiratory …, 2017 - Springer
Background Cigarette smoke (CS) is associated with lower numbers of circulating stem cells
and might severely affect their mobilization, trafficking and homing. Our study was designed …

Pulmonary inflammatory reaction and structural changes induced by cigarette smoke exposure in the Guinea pig

…, VI Peinado, R Puig-Pey… - COPD: Journal of …, 2012 - Taylor & Francis
Cigarette smoke (CS) induces an inflammatory process in the lung that may underlie the
development of chronic obstructive pulmonary disease (COPD). The nature and characteristics …

Sildenafil in a cigarette smoke-induced model of COPD in the guinea-pig

…, C Valdés, E Ferrer, R Puig-Pey… - European …, 2015 - Eur Respiratory Soc
Sildenafil, a phosphodiesterase-5 inhibitor used to treat pulmonary hypertension, may have
effects on pulmonary vessel structure and function. We evaluated the effects of sildenafil in a …

Effects of Aclidinium Bromide in a Cigarette Smoke–Exposed Guinea Pig Model of Chronic Obstructive Pulmonary Disease

D Domínguez-Fandos, E Ferrer, R Puig-Pey… - American Journal of …, 2014 - atsjournals.org
… Raquel Puig-Pey … Furthermore, the numbers of neutrophils and eosinophils infiltrating the
airways correlated with the wall thickness of smaller airways (r = 0.61, P = 0.002 and r = 0.66, P …

Iterative two-step genetic-algorithm-based method for efficient polynomial B-spline surface reconstruction

A Gálvez, A Iglesias, J Puig-Pey - Information Sciences, 2012 - Elsevier
Surface reconstruction is a very challenging problem arising in a wide variety of applications
such as CAD design, data visualization, virtual reality, medical imaging, computer animation…

[HTML][HTML] Multiparameter immune profiling of operational tolerance in liver transplantation

M Martínez-Llordella, I Puig-Pey, G Orlando… - American Journal of …, 2007 - Elsevier
Immunosuppressive drugs can be completely withdrawn in up to 20% of liver transplant
recipients, commonly referred to as ‘operationally’ tolerant. Immune characterization of these …

[HTML][HTML] Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients

…, JJ Lozano, I Puig-Pey… - The Journal of …, 2008 - Am Soc Clin Investig
A fraction of liver transplant recipients are able to discontinue all immunosuppressive therapies
without rejecting their grafts and are said to be operationally tolerant to the transplant. …

[HTML][HTML] ATG‐Fresenius treatment and low‐dose tacrolimus: results of a randomized controlled trial in liver transplantation

CE Benítez, I PuigPey, M López… - American journal of …, 2010 - Elsevier
We report the results of a prospective randomized controlled trial in liver transplantation
assessing the efficacy and safety of antithymocyte globulin (ATG‐Fresenius) plus tacrolimus …

Bézier curve and surface fitting of 3D point clouds through genetic algorithms, functional networks and least-squares approximation

A Gálvez, A Iglesias, A Cobo, J Puig-Pey… - … Science and Its …, 2007 - Springer
This work concerns the problem of curve and surface fitting. In particular, we focus on the
case of 3D point clouds fitted with Bézier curves and surfaces. Because these curves and …