Expression of xenobiotic-metabolizing CYPs in human pulmonary tissue

…, K Päivärinta, O Pelkonen, S Anttila, R Piipari… - Experimental and …, 1999 - Elsevier
The pattern of expression of individual cytochrome P450 (CYP) forms participating in the
metabolism of xenobiotics is being increasingly well characterised in the human pulmonary …

Smoking and asthma in adults

R Piipari, JJK Jaakkola, N Jaakkola… - European respiratory …, 2004 - Eur Respiratory Soc
Studies on the effect of smoking on adulthood asthma have provided contradictory results.
The current authors conducted a population-based incident case-control study to assess the …

Indoor dampness and molds and development of adult-onset asthma: a population-based incident case-control study.

MS Jaakkola, H Nordman, R Piipari, J Uitti… - Environmental …, 2002 - ehp.niehs.nih.gov
Previous cross-sectional and prevalent case-control studies have suggested increased risk
of asthma in adults related to dampness problems and molds in homes. We conducted a …

Environmental tobacco smoke and adult-onset asthma: a population-based incident case–control study

MS Jaakkola, R Piipari, N Jaakkola… - American Journal of …, 2003 - ajph.aphapublications.org
R. Piipari participated in acquisition of data, interpretation of data, and critical revision of
the article. N. Jaakkola participated in acquisition of data, analysis and interpretation of data, …

Occupation and asthma: a population-based incident case-control study

JJK Jaakkola, R Piipari… - American journal of …, 2003 - academic.oup.com
The authors assessed the relations between occupation and risk of developing asthma in
adulthood in a 1997–2000 population-based incident case-control study of 521 cases and 932 …

Regulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells

J Hukkanen, T Väisänen, A Lassila, R Piipari… - … of Pharmacology and …, 2003 - ASPET
CYP3A5 is the major CYP3A form in the human lung, and it is inducible by dexamethasone
in the human A549 lung adenocarcinoma cell line. In the present study, we characterized the …

Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon‐DNA adduct formation in bronchoalveolar macrophages of smokers and non …

R Piipari, K Savela, T Nurminen… - … journal of cancer, 2000 - Wiley Online Library
Variability in the expression of enzymes metabolizing carcinogens derived from cigarette
smoke may contribute to individual susceptibility to pulmonary carcinogenesis. This study was …

Occupational dermatitis and allergic respiratory diseases in Finnish metalworking machinists

…, R Piipari, T Tuomi, R Jolanki - Occupational …, 2007 - academic.oup.com
Aim To investigate the incidences and trends of occupational skin diseases (OSDs) and
allergic respiratory diseases (ARDs) in machinists working in the fabrication of metal products. …

Agents causing occupational asthma in Finland in 1986–2002: cow epithelium bypassed by moulds from moisture‐damaged buildings

R Piipari, H Keskinen - Clinical & Experimental Allergy, 2005 - Wiley Online Library
Background Occupational asthma is an avoidable form of asthma. In Finland, the diagnosis
of occupational asthma entitles substantial compensation to the employee. The diagnostics …

Pets, parental atopy, and asthma in adults

JJK Jaakkola, N Jaakkola, R Piipari… - Journal of allergy and …, 2002 - Elsevier
Background: Studies of exposure to pets and the risk of asthma have provided conflicting
results. Objective: We conducted a population-based incident case-control study to assess the …